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- Genome_engineering abstract "Genome engineering refers to the strategies and techniques developed in recent years for the targeted, specific modification of the genetic information – or genome – of living organisms.It represents a very active field of research because of the wide range of possible applications, particularly in the areas of human health - the correction of a gene carrying a harmful mutation, the production of therapeutic proteins, the elimination of persistent viral sequences - agricultural biotechnology - the development of new generations of genetically modified plants - and for the development of research tools - for example, to explore the function of a gene.Early technologies developed to insert a gene into a living cell, such as transgenesis, are limited by the random nature of the insertion of the new sequence into the genome. The new gene is positioned blindly, and may inactivate or disturb the functioning of other genes or even cause severe unwanted effects; it may trigger a process of cancerization, for example. Furthermore, these technologies offer no degree of reproducibility, as there is no guarantee that the new sequence will be inserted at the same place in two different cells.The major advantage of genome engineering, which uses more recent knowledge and technology, is that it enables a specific area of the DNA to be modified, thereby increasing the precision of the correction or insertion, preventing any cell toxicity and offering perfect reproducibility.Genome engineering and synthetic genomics (designing artificial genomes) are currently among the most promising technologies in terms of applied biological research and industrial innovation.".
- Genome_engineering thumbnail MAGE.jpg?width=300.
- Genome_engineering wikiPageExternalLink faq.php.
- Genome_engineering wikiPageExternalLink www.cellectis.com.
- Genome_engineering wikiPageExternalLink startCas9.
- Genome_engineering wikiPageExternalLink ngec.
- Genome_engineering wikiPageExternalLink www.zincfingers.org.
- Genome_engineering wikiPageID "29482412".
- Genome_engineering wikiPageRevisionID "600266988".
- Genome_engineering hasPhotoCollection Genome_engineering.
- Genome_engineering subject Category:Genetic_engineering.
- Genome_engineering subject Category:Genomics.
- Genome_engineering comment "Genome engineering refers to the strategies and techniques developed in recent years for the targeted, specific modification of the genetic information – or genome – of living organisms.It represents a very active field of research because of the wide range of possible applications, particularly in the areas of human health - the correction of a gene carrying a harmful mutation, the production of therapeutic proteins, the elimination of persistent viral sequences - agricultural biotechnology - the development of new generations of genetically modified plants - and for the development of research tools - for example, to explore the function of a gene.Early technologies developed to insert a gene into a living cell, such as transgenesis, are limited by the random nature of the insertion of the new sequence into the genome. ".
- Genome_engineering label "Genome engineering".
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- Genome_engineering sameAs Q5533490.
- Genome_engineering sameAs Q5533490.
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