Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Genotoxicity> ?p ?o. }
Showing items 1 to 30 of
30
with 100 items per page.
- Genotoxicity abstract "In genetics, genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer. While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, however, not all genotoxic substances are mutagenic. The alteration can have direct or indirect effects on the DNA: the induction of mutations, mistimed event activation, and direct DNA damage leading to mutations. The permanent, heritable changes can affect either somatic cells of the organism or germ cells to be passed on to future generations. Cells prevent expression of the genotoxic mutation by either DNA repair or apoptosis; however, the damage may not always be fixed leading to mutagenesis.To assay for genotoxic molecules, researchers assay for DNA damage in cells exposed to the toxic substrates. This DNA damage can be in the form of single- and double-strand breaks, loss of excision repair, cross-linking, alkali-labile sites, point mutations, and structural and numerical chromosomal aberrations. The compromised integrity of the genetic material has been known to cause cancer. As a consequence, many sophisticated techniques including Ames Assay, in vitro and in vivo Toxicology Tests, and Comet Assay have been developed to assess the chemicals' potential to cause DNA damage that may lead to cancer.".
- Genotoxicity thumbnail Ssvsds.jpg?width=300.
- Genotoxicity wikiPageID "632874".
- Genotoxicity wikiPageRevisionID "597721247".
- Genotoxicity hasPhotoCollection Genotoxicity.
- Genotoxicity subject Category:Carcinogenesis.
- Genotoxicity subject Category:Mutation.
- Genotoxicity comment "In genetics, genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer. While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, however, not all genotoxic substances are mutagenic. The alteration can have direct or indirect effects on the DNA: the induction of mutations, mistimed event activation, and direct DNA damage leading to mutations.".
- Genotoxicity label "Genotoksyczność".
- Genotoxicity label "Genotossicità".
- Genotoxicity label "Genotoxicidad".
- Genotoxicity label "Genotoxicidade".
- Genotoxicity label "Genotoxicity".
- Genotoxicity label "Genotoxizität".
- Genotoxicity label "Génotoxique".
- Genotoxicity label "Генотоксичность".
- Genotoxicity label "سمية جينية".
- Genotoxicity label "基因毒性".
- Genotoxicity sameAs Genotoxizität.
- Genotoxicity sameAs Genotoxicidad.
- Genotoxicity sameAs Génotoxique.
- Genotoxicity sameAs Genotossicità.
- Genotoxicity sameAs Genotoksyczność.
- Genotoxicity sameAs Genotoxicidade.
- Genotoxicity sameAs m.02ytvr.
- Genotoxicity sameAs Q1009245.
- Genotoxicity sameAs Q1009245.
- Genotoxicity wasDerivedFrom Genotoxicity?oldid=597721247.
- Genotoxicity depiction Ssvsds.jpg.
- Genotoxicity isPrimaryTopicOf Genotoxicity.