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- Geranylgeranylation abstract "Geranylgeranylation is a form of prenylation, which is a post-translational modification of proteins that involves the attachment of one or two 20-carbon lipophilic geranylgeranyl isoprene units from geranylgeranyl diphosphate to one or two cysteine residue(s) at the C-terminus of specific proteins. Prenylation (including geranylgeranylation) is thought to function, at least in part, as a membrane anchor for proteins.The process of geranylgeranylation can be catalyzed by either geranylgeranyl transferase I (GGTase I) or Rab GGTase (also GGTase II). GGTase I catalyzes the addition of one geranylgeranyl group onto the C-terminal consensus sequence CAAL (somewhat similar to farnesyltransferase reactions), where C=cysteine, A=any aliphatic amino acid, and L=leucine. Rab GGTase adds a total of two geranylgeranyl groups onto two cysteine residues at the C-terminal consensus sequence CXC or XXCC. The source of the geranylgeranyl group is geranylgeranyl diphosphate, which is synthesized from the isoprenoid biosynthetic pathway. An example of this can be seen in the lipid anchoring of the Rho GTPase family of signaling molecules and the gamma subunit of heterotrimeric G proteins.".
- Geranylgeranylation wikiPageID "10175256".
- Geranylgeranylation wikiPageRevisionID "557727170".
- Geranylgeranylation hasPhotoCollection Geranylgeranylation.
- Geranylgeranylation subject Category:Gene_expression.
- Geranylgeranylation subject Category:Molecular_biology.
- Geranylgeranylation subject Category:Proteins.
- Geranylgeranylation type Abstraction100002137.
- Geranylgeranylation type Chemical114806838.
- Geranylgeranylation type Compound114818238.
- Geranylgeranylation type Macromolecule114944888.
- Geranylgeranylation type Material114580897.
- Geranylgeranylation type Matter100020827.
- Geranylgeranylation type Molecule114682133.
- Geranylgeranylation type OrganicCompound114727670.
- Geranylgeranylation type Part113809207.
- Geranylgeranylation type PhysicalEntity100001930.
- Geranylgeranylation type Protein114728724.
- Geranylgeranylation type Proteins.
- Geranylgeranylation type Relation100031921.
- Geranylgeranylation type Substance100019613.
- Geranylgeranylation type Thing100002452.
- Geranylgeranylation type Unit109465459.
- Geranylgeranylation comment "Geranylgeranylation is a form of prenylation, which is a post-translational modification of proteins that involves the attachment of one or two 20-carbon lipophilic geranylgeranyl isoprene units from geranylgeranyl diphosphate to one or two cysteine residue(s) at the C-terminus of specific proteins.".
- Geranylgeranylation label "Geranylgeranylation".
- Geranylgeranylation sameAs m.02q465z.
- Geranylgeranylation sameAs Q5549891.
- Geranylgeranylation sameAs Q5549891.
- Geranylgeranylation sameAs Geranylgeranylation.
- Geranylgeranylation wasDerivedFrom Geranylgeranylation?oldid=557727170.
- Geranylgeranylation isPrimaryTopicOf Geranylgeranylation.