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- Giant-cell_tumor_of_bone abstract "Giant-cell tumor of the bone (GCTOB) is a relatively uncommon tumor of the bone. It is characterized by the presence of multinucleated giant cells (osteoclast-like cells). Malignancy in giant cell tumor is uncommon and occurs in approximately 2% of all cases. However, if malignant degeneration does occur it is likely to metastasize to the lungs. Giant cell tumors are normally benign, with unpredictable behavior. It is a heterogeneous tumor composed of three different cell populations. The giant-cell tumour stromal cells (GCTSC) constitute the neoplastic cells, which are from an osteoblastic origin and are classified based on expression of osteoblast cell markers such as alkaline phosphatase and ostocalsin. In contrast, the mononuclear histiocytic cells (MNHC) and multinucleated giant cell (MNGC) fractions are secondarily recruited and comprise the non-neoplastic cell population. They are derived from an osteoclast-monocyte lineage determined primarily by expression of CD68, a marker for monocytic precursor cells. In most patients, the tumors are slow to develop, but may recur locally in as many as 50% of cases.".
- Giant-cell_tumor_of_bone diseasesdb "9337".
- Giant-cell_tumor_of_bone emedicineSubject "radio".
- Giant-cell_tumor_of_bone emedicineTopic "307".
- Giant-cell_tumor_of_bone icd10 "C40, C41".
- Giant-cell_tumor_of_bone icdo "9250/1".
- Giant-cell_tumor_of_bone meshId "D018212".
- Giant-cell_tumor_of_bone thumbnail Giant_cell_tumour_of_bone_-_high_mag.jpg?width=300.
- Giant-cell_tumor_of_bone wikiPageExternalLink giantcelltumor.ning.com.
- Giant-cell_tumor_of_bone wikiPageExternalLink top.
- Giant-cell_tumor_of_bone wikiPageExternalLink showBackIssue.asp?issn=0019-5413;year=2007;volume=41;issue=2;month=April-June.
- Giant-cell_tumor_of_bone wikiPageExternalLink watch?v=hoWIcZ0eA9A.
- Giant-cell_tumor_of_bone wikiPageID "3121384".
- Giant-cell_tumor_of_bone wikiPageRevisionID "604630796".
- Giant-cell_tumor_of_bone caption "Micrograph of a giant-cell tumor of bone showing the characteristic giant cells. H&E stain.".
- Giant-cell_tumor_of_bone diseasesdb "9337".
- Giant-cell_tumor_of_bone emedicinesubj "radio".
- Giant-cell_tumor_of_bone emedicinetopic "307".
- Giant-cell_tumor_of_bone hasPhotoCollection Giant-cell_tumor_of_bone.
- Giant-cell_tumor_of_bone icd "C40, C41".
- Giant-cell_tumor_of_bone icdo "9250".
- Giant-cell_tumor_of_bone meshid "D018212".
- Giant-cell_tumor_of_bone name "Giant-cell tumor of bone".
- Giant-cell_tumor_of_bone subject Category:Osseous_and_chondromatous_neoplasia.
- Giant-cell_tumor_of_bone type Abstraction100002137.
- Giant-cell_tumor_of_bone type Attribute100024264.
- Giant-cell_tumor_of_bone type Condition113920835.
- Giant-cell_tumor_of_bone type Disease114070360.
- Giant-cell_tumor_of_bone type IllHealth114052046.
- Giant-cell_tumor_of_bone type Illness114061805.
- Giant-cell_tumor_of_bone type PathologicalState114051917.
- Giant-cell_tumor_of_bone type PhysicalCondition114034177.
- Giant-cell_tumor_of_bone type State100024720.
- Giant-cell_tumor_of_bone type Disease.
- Giant-cell_tumor_of_bone type Situation.
- Giant-cell_tumor_of_bone comment "Giant-cell tumor of the bone (GCTOB) is a relatively uncommon tumor of the bone. It is characterized by the presence of multinucleated giant cells (osteoclast-like cells). Malignancy in giant cell tumor is uncommon and occurs in approximately 2% of all cases. However, if malignant degeneration does occur it is likely to metastasize to the lungs. Giant cell tumors are normally benign, with unpredictable behavior. It is a heterogeneous tumor composed of three different cell populations.".
- Giant-cell_tumor_of_bone label "Giant-cell tumor of bone".
- Giant-cell_tumor_of_bone label "Guz olbrzymiokomórkowy kości".
- Giant-cell_tumor_of_bone label "Osteoclastoma".
- Giant-cell_tumor_of_bone label "Riesenzelltumor".
- Giant-cell_tumor_of_bone label "Tumor ósseo de células gigantes".
- Giant-cell_tumor_of_bone label "Гигантоклеточная опухоль".
- Giant-cell_tumor_of_bone sameAs Riesenzelltumor.
- Giant-cell_tumor_of_bone sameAs Osteoclastoma.
- Giant-cell_tumor_of_bone sameAs Guz_olbrzymiokomórkowy_kości.
- Giant-cell_tumor_of_bone sameAs Tumor_ósseo_de_células_gigantes.
- Giant-cell_tumor_of_bone sameAs m.08stjc.
- Giant-cell_tumor_of_bone sameAs Q1785791.
- Giant-cell_tumor_of_bone sameAs Q1785791.
- Giant-cell_tumor_of_bone sameAs Giant-cell_tumor_of_bone.
- Giant-cell_tumor_of_bone wasDerivedFrom Giant-cell_tumor_of_bone?oldid=604630796.
- Giant-cell_tumor_of_bone depiction Giant_cell_tumour_of_bone_-_high_mag.jpg.
- Giant-cell_tumor_of_bone isPrimaryTopicOf Giant-cell_tumor_of_bone.
- Giant-cell_tumor_of_bone name "Giant-cell tumor of bone".