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- Gideon_Dreyfuss abstract "Dr. Gideon Dreyfuss is the Isaac Norris Professor of Biochemistry and Biophysics at the University of Pennsylvania School of Medicine and an investigator of the Howard Hughes Medical Institute. He was elected to the National Academy of Sciences in 2012.He received his Ph.D. in biological chemistry in 1978 from Harvard University. Dr. Dreyfuss is a fellow of the American Academy of Arts and Sciences.The Dreyfuss Lab is interested in various projects studying the function and biogenesis of non-coding RNA and the proteins that interact with RNA. A primary research goal of the lab is to elucidate the function of Survival of Motor Neuron protein, SMN, which assembles a heptameric ring of Sm proteins on U snRNAs to form snRNPs that are essential components of the splicesome. Moreover, loss of functional SMN is directly linked to spinal muscular atrophy, a debilitating neurodegenerative disease that is characterize by the eventual death of motor neurons and muscular wasting. The Dreyfuss Lab is conducting research to understand the role of SMN in SMA pathology and using high throughput screening to discover potential therapeutics. The lab also studies the dynamic mechanism of RNA splicing, the RNA-binding proteins that determine exonic specificity, and snRNAs that are important regulators of splicing and mRNA maturation.".
- Gideon_Dreyfuss almaMater Harvard_University.
- Gideon_Dreyfuss almaMater Hebrew_University_of_Jerusalem.
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- Gideon_Dreyfuss birthPlace New_York.
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- Gideon_Dreyfuss birthPlace United_States.
- Gideon_Dreyfuss field Biochemistry.
- Gideon_Dreyfuss field Molecular_biology.
- Gideon_Dreyfuss knownFor Heterogeneous_ribonucleoprotein_particle.
- Gideon_Dreyfuss knownFor Spinal_muscular_atrophy.
- Gideon_Dreyfuss knownFor Survival_of_motor_neuron.
- Gideon_Dreyfuss nationality United_States.
- Gideon_Dreyfuss residence Pennsylvania.
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- Gideon_Dreyfuss almaMater Harvard_University.
- Gideon_Dreyfuss almaMater Hebrew_University_of_Jerusalem.
- Gideon_Dreyfuss almaMater "Massachusetts Institute of Technology".
- Gideon_Dreyfuss birthPlace New_York.
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- Gideon_Dreyfuss field Biochemistry.
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- Gideon_Dreyfuss knownFor "Discovering and naming several hnRNP's and the proteins associated with SMN, for which loss of function is the primary cause of SMA,".
- Gideon_Dreyfuss name "Dreyfuss, Gideon".
- Gideon_Dreyfuss name "Gideon Dreyfuss".
- Gideon_Dreyfuss nationality United_States.
- Gideon_Dreyfuss placeOfBirth New_York.
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- Gideon_Dreyfuss postdoctoralAdvisor David_Baltimore.
- Gideon_Dreyfuss religion "Jewish".
- Gideon_Dreyfuss residence Pennsylvania.
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- Gideon_Dreyfuss shortDescription "American biochemist".
- Gideon_Dreyfuss workInstitution Northwestern_University.
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- Gideon_Dreyfuss comment "Dr. Gideon Dreyfuss is the Isaac Norris Professor of Biochemistry and Biophysics at the University of Pennsylvania School of Medicine and an investigator of the Howard Hughes Medical Institute. He was elected to the National Academy of Sciences in 2012.He received his Ph.D. in biological chemistry in 1978 from Harvard University. Dr.".
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