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- Gliotoxin abstract "Gliotoxin is a sulfur-containing mycotoxin produced by several species of fungi, including pathogens of humans such as Aspergillus fumigatus, and also by species of Trichoderma, and Penicillium. Gliotoxin has also been reported from yeasts of the genus Candida, but results from other studies have cast doubt on the production of this metabolite by Candida fungi. Gliotoxin was originally isolated from Gliocladium fimbriatum, and was named accordingly. It is an epipolythiodioxopiperazine metabolite.Gliotoxin possesses immunosuppressive properties as it may suppress and cause apoptosis in certain types of cells of the immune system, including neutrophils, eosinophils, granulocytes, macrophages, and thymocytes. It also acts as an inhibitor of farnesyl transferase. It noncompetitively inhibits the chymotrypsin-like activity of the 20S proteasome. In vivo it displays anti-inflammatory activity. It acts by blocking thiol groups in the cell membranes. It was investigated as an antibiotic and antifungal in the 1940s and recently as an antiviral agent.".
- Gliotoxin iupacName "(3R,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-2,3,6,10-tetrahydro-5aH-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione".
- Gliotoxin thumbnail Gliotoxin.png?width=300.
- Gliotoxin wikiPageExternalLink abstract.
- Gliotoxin wikiPageExternalLink Gliotoxin-MSDS.htm.
- Gliotoxin wikiPageExternalLink gliotoxin.htm.
- Gliotoxin wikiPageID "8016328".
- Gliotoxin wikiPageRevisionID "604384655".
- Gliotoxin c "13".
- Gliotoxin h "14".
- Gliotoxin hasPhotoCollection Gliotoxin.
- Gliotoxin imagefile "Gliotoxin.png".
- Gliotoxin iupacname "-6".
- Gliotoxin n "2".
- Gliotoxin o "4".
- Gliotoxin s "2".
- Gliotoxin verifiedrevid "441932116".
- Gliotoxin watchedfields "changed".
- Gliotoxin subject Category:Alcohols.
- Gliotoxin subject Category:Antibiotics.
- Gliotoxin subject Category:Immunosuppressants.
- Gliotoxin subject Category:Indoles.
- Gliotoxin subject Category:Lactams.
- Gliotoxin subject Category:Mycotoxins.
- Gliotoxin type Agent114778436.
- Gliotoxin type Antibacterial102716205.
- Gliotoxin type Antibiotic102716866.
- Gliotoxin type Antibiotics.
- Gliotoxin type CausalAgent100007347.
- Gliotoxin type Drug103247620.
- Gliotoxin type Immunosuppressant103562958.
- Gliotoxin type Immunosuppressants.
- Gliotoxin type Matter100020827.
- Gliotoxin type Medicine103740161.
- Gliotoxin type Mycotoxin115036536.
- Gliotoxin type Mycotoxins.
- Gliotoxin type PhysicalEntity100001930.
- Gliotoxin type PlantToxin115036638.
- Gliotoxin type Poison115032376.
- Gliotoxin type Substance100020090.
- Gliotoxin type Toxin115034074.
- Gliotoxin type ChemicalCompound.
- Gliotoxin type ChemicalSubstance.
- Gliotoxin type ChemicalSubstanceType.
- Gliotoxin type ChemicalObject.
- Gliotoxin type Thing.
- Gliotoxin comment "Gliotoxin is a sulfur-containing mycotoxin produced by several species of fungi, including pathogens of humans such as Aspergillus fumigatus, and also by species of Trichoderma, and Penicillium. Gliotoxin has also been reported from yeasts of the genus Candida, but results from other studies have cast doubt on the production of this metabolite by Candida fungi. Gliotoxin was originally isolated from Gliocladium fimbriatum, and was named accordingly.".
- Gliotoxin label "Gliotoxin".
- Gliotoxin label "Gliotoxin".
- Gliotoxin label "Gliotoxina".
- Gliotoxin sameAs Gliotoxin.
- Gliotoxin sameAs Gliotoxina.
- Gliotoxin sameAs m.026nndv.
- Gliotoxin sameAs Q413364.
- Gliotoxin sameAs Q413364.
- Gliotoxin sameAs Gliotoxin.
- Gliotoxin wasDerivedFrom Gliotoxin?oldid=604384655.
- Gliotoxin depiction Gliotoxin.png.
- Gliotoxin isPrimaryTopicOf Gliotoxin.