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- GlmS_glucosamine-6-phosphate_activated_ribozyme abstract "The Glucosamine-6-phosphate activated ribozyme ( glmS ribozyme) is an RNA structure that is both a ribozyme, since it catalyzes a chemical reaction, and a riboswitch, since it regulates genes in response to concentrations of a metabolite.It was originally identified using bioinformatics in the 5' untranslated regions of glmS genes.The GlmS enzyme catalyzes the production of glucosamine-6-phosphate (GlcN6P), and the glmS ribozyme is dependent on GlcN6P to achieve catalysis of its own cleavage. This cleavage leads to the degradation of the mRNA that contains the ribozyme, and ultimately lowers production of the GlmS enzyme, encoded by the glmS gene. The GlmS enzyme catalyzes the reaction to synthesize GlcN6P, so it is not required when GlcN6P levels are already high. When GlcN6P levels are low, the ribozyme does not cleave, allowing production of the GlmS enzyme, and ultimately more GlcN6P. In fact, GlcN6P is a cofactor for the cleavage reaction, as it directly participates in the chemical reaction as an acid-base catalyst.".
- GlmS_glucosamine-6-phosphate_activated_ribozyme thumbnail GlmS_ribozyme_secondary_structure.jpg?width=300.
- GlmS_glucosamine-6-phosphate_activated_ribozyme wikiPageID "11420863".
- GlmS_glucosamine-6-phosphate_activated_ribozyme wikiPageRevisionID "591472016".
- GlmS_glucosamine-6-phosphate_activated_ribozyme caption "Predicted secondary structure and sequence conservation of glmS".
- GlmS_glucosamine-6-phosphate_activated_ribozyme hasPhotoCollection GlmS_glucosamine-6-phosphate_activated_ribozyme.
- GlmS_glucosamine-6-phosphate_activated_ribozyme id "RF00234".
- GlmS_glucosamine-6-phosphate_activated_ribozyme name "glmS glucosamine-6-phosphate activated ribozyme".
- GlmS_glucosamine-6-phosphate_activated_ribozyme rfam "RF00234".
- GlmS_glucosamine-6-phosphate_activated_ribozyme rnaType Cis-regulatory_element.
- GlmS_glucosamine-6-phosphate_activated_ribozyme rnaType Riboswitch.
- GlmS_glucosamine-6-phosphate_activated_ribozyme symbol "glmS".
- GlmS_glucosamine-6-phosphate_activated_ribozyme taxDomain Bacteria.
- GlmS_glucosamine-6-phosphate_activated_ribozyme subject Category:Cis-regulatory_RNA_elements.
- GlmS_glucosamine-6-phosphate_activated_ribozyme subject Category:Riboswitch.
- GlmS_glucosamine-6-phosphate_activated_ribozyme subject Category:Ribozymes.
- GlmS_glucosamine-6-phosphate_activated_ribozyme comment "The Glucosamine-6-phosphate activated ribozyme ( glmS ribozyme) is an RNA structure that is both a ribozyme, since it catalyzes a chemical reaction, and a riboswitch, since it regulates genes in response to concentrations of a metabolite.It was originally identified using bioinformatics in the 5' untranslated regions of glmS genes.The GlmS enzyme catalyzes the production of glucosamine-6-phosphate (GlcN6P), and the glmS ribozyme is dependent on GlcN6P to achieve catalysis of its own cleavage.".
- GlmS_glucosamine-6-phosphate_activated_ribozyme label "GlmS glucosamine-6-phosphate activated ribozyme".
- GlmS_glucosamine-6-phosphate_activated_ribozyme sameAs m.02rbxz0.
- GlmS_glucosamine-6-phosphate_activated_ribozyme sameAs Q5570005.
- GlmS_glucosamine-6-phosphate_activated_ribozyme sameAs Q5570005.
- GlmS_glucosamine-6-phosphate_activated_ribozyme wasDerivedFrom GlmS_glucosamine-6-phosphate_activated_ribozyme?oldid=591472016.
- GlmS_glucosamine-6-phosphate_activated_ribozyme depiction GlmS_ribozyme_secondary_structure.jpg.
- GlmS_glucosamine-6-phosphate_activated_ribozyme isPrimaryTopicOf GlmS_glucosamine-6-phosphate_activated_ribozyme.