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- Glucokinase abstract "Glucokinase (EC 2.7.1.2) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Glucokinase occurs in cells in the liver, pancreas, gut, and brain of humans and most other vertebrates. In each of these organs it plays an important role in the regulation of carbohydrate metabolism by acting as a glucose sensor, triggering shifts in metabolism or cell function in response to rising or falling levels of glucose, such as occur after a meal or when fasting. Mutations of the gene for this enzyme can cause unusual forms of diabetes or hypoglycemia.Glucokinase (GK) is a hexokinase isozyme, related homologously to at least three other hexokinases. All of the hexokinases can mediate phosphorylation of glucose to glucose-6-phosphate (G6P), which is the first step of both glycogen synthesis and glycolysis. However, glucokinase is coded by a separate gene and its distinctive kinetic properties allow it to serve a different set of functions. Glucokinase has a lower affinity for glucose than the other hexokinases do, and its activity is localized to a few cell types, leaving the other three hexokinases as more important preparers of glucose for glycolysis and glycogen synthesis for most tissues and organs. Because of this reduced affinity, the activity of glucokinase, under usual physiological conditions, varies substantially according to the concentration of glucose.".
- Glucokinase entrezgene "2645".
- Glucokinase symbol "Glucokinase".
- Glucokinase wikiPageExternalLink nicezyme.pl?2.7.1.2.
- Glucokinase wikiPageExternalLink NBK1375.
- Glucokinase wikiPageExternalLink NBK1447.
- Glucokinase wikiPageExternalLink TOC.
- Glucokinase wikiPageID "549614".
- Glucokinase wikiPageRevisionID "604385950".
- Glucokinase caption "Structures of Escherichia coli ATP-dependent glucokinase.".
- Glucokinase casNumber "9001".
- Glucokinase ecNumber "2.7".
- Glucokinase goCode "4340".
- Glucokinase hasPhotoCollection Glucokinase.
- Glucokinase interpro "IPR003836".
- Glucokinase iubmbEcNumber "2".
- Glucokinase name "Glucokinase".
- Glucokinase pdb ", , ,".
- Glucokinase pfam "PF02685".
- Glucokinase pfamClan "CL0108".
- Glucokinase requireManualInspection "no".
- Glucokinase scop "1".
- Glucokinase symbol "Glucokinase".
- Glucokinase updateCitations "no".
- Glucokinase updatePage "yes".
- Glucokinase updateProteinBox "yes".
- Glucokinase updateSummary "no".
- Glucokinase subject Category:EC_2.7.1.
- Glucokinase subject Category:Protein_families.
- Glucokinase type Abstraction100002137.
- Glucokinase type Family108078020.
- Glucokinase type Group100031264.
- Glucokinase type Organization108008335.
- Glucokinase type ProteinFamilies.
- Glucokinase type SocialGroup107950920.
- Glucokinase type Unit108189659.
- Glucokinase type YagoLegalActor.
- Glucokinase type YagoLegalActorGeo.
- Glucokinase type YagoPermanentlyLocatedEntity.
- Glucokinase type Biomolecule.
- Glucokinase type Protein.
- Glucokinase type BiologicalObject.
- Glucokinase comment "Glucokinase (EC 2.7.1.2) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Glucokinase occurs in cells in the liver, pancreas, gut, and brain of humans and most other vertebrates. In each of these organs it plays an important role in the regulation of carbohydrate metabolism by acting as a glucose sensor, triggering shifts in metabolism or cell function in response to rising or falling levels of glucose, such as occur after a meal or when fasting.".
- Glucokinase label "Glucochinasi".
- Glucokinase label "Glucokinase".
- Glucokinase label "Glucokinase".
- Glucokinase label "Glucokinase".
- Glucokinase label "Glukokinaza".
- Glucokinase label "Глюкокиназа".
- Glucokinase label "غلوكوكيناز".
- Glucokinase sameAs Glucokinase.
- Glucokinase sameAs Glucokinase.
- Glucokinase sameAs Glucochinasi.
- Glucokinase sameAs Glukokinaza.
- Glucokinase sameAs m.02p024.
- Glucokinase sameAs Q425185.
- Glucokinase sameAs Q425185.
- Glucokinase sameAs 1675.
- Glucokinase sameAs 4662.
- Glucokinase sameAs Glucokinase.
- Glucokinase wasDerivedFrom Glucokinase?oldid=604385950.
- Glucokinase isPrimaryTopicOf Glucokinase.