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- Glycine_riboswitch abstract "The bacterial glycine riboswitch is an RNA element that can bind the amino acid glycine. Glycine riboswitches usually consist of two metabolite-binding aptamer domains with similar structures in tandem. The aptamers cooperatively bind glycine to regulate the expression of downstream genes. In Bacillus subtilis, this riboswitch is found upstream of the gcvT operon which controls glycine degradation. It is thought that when glycine is in excess it will bind to both aptamers to activate these genes and facilitate glycine degradation.A truncated version of the glycine riboswitch exhibits sigmoidal binding curves with Hill coefficients greater than one, which led to the idea of positive cooperativity between the two aptamer domains. Data in 2012 shows that cooperative binding does not occur in the switch with its extended 5' leader, though the purpose of the dual aptamer switch is still uncertain.".
- Glycine_riboswitch thumbnail RF00504.jpg?width=300.
- Glycine_riboswitch wikiPageID "11420868".
- Glycine_riboswitch wikiPageRevisionID "547722936".
- Glycine_riboswitch altsymbols "gcvT".
- Glycine_riboswitch caption "Predicted secondary structure and sequence conservation of Glycine".
- Glycine_riboswitch hasPhotoCollection Glycine_riboswitch.
- Glycine_riboswitch id "RF00504".
- Glycine_riboswitch name "Glycine riboswitch".
- Glycine_riboswitch rfam "RF00504".
- Glycine_riboswitch rnaType Cis-regulatory_element.
- Glycine_riboswitch rnaType Riboswitch.
- Glycine_riboswitch symbol "Glycine".
- Glycine_riboswitch taxDomain Bacteria.
- Glycine_riboswitch subject Category:Cis-regulatory_RNA_elements.
- Glycine_riboswitch subject Category:Riboswitch.
- Glycine_riboswitch type Abstraction100002137.
- Glycine_riboswitch type Cis-regulatoryRNAElements.
- Glycine_riboswitch type Cognition100023271.
- Glycine_riboswitch type Component105868954.
- Glycine_riboswitch type Concept105835747.
- Glycine_riboswitch type Content105809192.
- Glycine_riboswitch type Idea105833840.
- Glycine_riboswitch type Part105867413.
- Glycine_riboswitch type PsychologicalFeature100023100.
- Glycine_riboswitch comment "The bacterial glycine riboswitch is an RNA element that can bind the amino acid glycine. Glycine riboswitches usually consist of two metabolite-binding aptamer domains with similar structures in tandem. The aptamers cooperatively bind glycine to regulate the expression of downstream genes. In Bacillus subtilis, this riboswitch is found upstream of the gcvT operon which controls glycine degradation.".
- Glycine_riboswitch label "Glycine riboswitch".
- Glycine_riboswitch sameAs m.02rbx_1.
- Glycine_riboswitch sameAs Q5572585.
- Glycine_riboswitch sameAs Q5572585.
- Glycine_riboswitch sameAs Glycine_riboswitch.
- Glycine_riboswitch wasDerivedFrom Glycine_riboswitch?oldid=547722936.
- Glycine_riboswitch depiction RF00504.jpg.
- Glycine_riboswitch isPrimaryTopicOf Glycine_riboswitch.