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- Gusperimus abstract "Gusperimus is an immunosuppressive drug. It is a derivative of the antitumor antibiotic spergualin, and inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells.Gusperimus was developed by Bristol-Myers Squibb. Currently, it is manufactured and sponsored for use as an orphan drug and for clinical studies by the Japanese company Euro Nippon Kayaku. The patent claim (see quotation) is that Gusperimus may be useful for a variety of hyperreactive inflammatory diseases such as autoimmune diseases. The drug is available in vials containing 100 mg each.There is little information about the pharmacokinetic properties of gusperimus.".
- Gusperimus thumbnail Gusperimus.svg?width=300.
- Gusperimus wikiPageExternalLink o034.htm.
- Gusperimus wikiPageExternalLink treatmentDetail.asp?treatmentID=858.
- Gusperimus wikiPageExternalLink nci_Gusperimus.
- Gusperimus wikiPageExternalLink art00040.
- Gusperimus wikiPageID "6249798".
- Gusperimus wikiPageRevisionID "572512858".
- Gusperimus hasPhotoCollection Gusperimus.
- Gusperimus imagefile "Gusperimus.svg".
- Gusperimus imagename "Skeletal formula of a gusperimus minor tautomer".
- Gusperimus othername "N-[2-[4-butylamino]-1-hydroxy-2-oxoethyl]-7-heptanamide".
- Gusperimus verifiedfields "changed".
- Gusperimus verifiedrevid "480476938".
- Gusperimus watchedfields "changed".
- Gusperimus subject Category:Guanidines.
- Gusperimus subject Category:Immunosuppressants.
- Gusperimus subject Category:Orphan_drugs.
- Gusperimus type Agent114778436.
- Gusperimus type CausalAgent100007347.
- Gusperimus type Drug103247620.
- Gusperimus type Immunosuppressant103562958.
- Gusperimus type Immunosuppressants.
- Gusperimus type Matter100020827.
- Gusperimus type Medicine103740161.
- Gusperimus type OrphanDrugs.
- Gusperimus type PhysicalEntity100001930.
- Gusperimus type Substance100020090.
- Gusperimus type ChemicalCompound.
- Gusperimus type ChemicalSubstance.
- Gusperimus type DrugProduct.
- Gusperimus type ChemicalObject.
- Gusperimus type Thing.
- Gusperimus comment "Gusperimus is an immunosuppressive drug. It is a derivative of the antitumor antibiotic spergualin, and inhibits the interleukin-2-stimulated maturation of T cells to the S and G2/M phases and the polarization of the T cells into IFN-gamma-secreting Th1 effector T cells, resulting in the inhibition of growth of activated naive CD4 T cells.Gusperimus was developed by Bristol-Myers Squibb.".
- Gusperimus label "Gusperimus".
- Gusperimus sameAs m.0fywq_.
- Gusperimus sameAs Q10910504.
- Gusperimus sameAs Q10910504.
- Gusperimus sameAs Gusperimus.
- Gusperimus wasDerivedFrom Gusperimus?oldid=572512858.
- Gusperimus depiction Gusperimus.svg.
- Gusperimus isPrimaryTopicOf Gusperimus.