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- HNF1B abstract "HNF1 homeobox B (hepatocyte nuclear factor 1 homeobox B), also known as HNF1B or transcription factor 2 (TCF2), is a human gene.TCF2 encodes transcription factor 2, a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.".
- HNF1B entrezgene "6928".
- HNF1B wikiPageID "14147496".
- HNF1B wikiPageRevisionID "545024653".
- HNF1B hasPhotoCollection HNF1B.
- HNF1B requireManualInspection "no".
- HNF1B summaryText "TCF2 encodes transcription factor 2, a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 . A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.".
- HNF1B updateCitations "yes".
- HNF1B updatePage "yes".
- HNF1B updateProteinBox "yes".
- HNF1B updateSummary "yes".
- HNF1B subject Category:Transcription_factors.
- HNF1B type Biomolecule.
- HNF1B type Protein.
- HNF1B type BiologicalObject.
- HNF1B comment "HNF1 homeobox B (hepatocyte nuclear factor 1 homeobox B), also known as HNF1B or transcription factor 2 (TCF2), is a human gene.TCF2 encodes transcription factor 2, a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes.".
- HNF1B label "HNF1B".
- HNF1B label "Transkriptionsfaktor 2".
- HNF1B sameAs Transkriptionsfaktor_2.
- HNF1B sameAs m.03cw1sw.
- HNF1B sameAs Q1522265.
- HNF1B sameAs Q1522265.
- HNF1B sameAs TCF2.
- HNF1B wasDerivedFrom HNF1B?oldid=545024653.
- HNF1B isPrimaryTopicOf HNF1B.