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- Heavy_chain_disease abstract "Heavy chain disease is a form of paraproteinemia with a proliferation of cells producing immunoglobulin heavy chains.This disease is characterized by an excessive production of heavy chains that are short and truncated. These heavy chain disease proteins have various deletions, mainly in their amino-terminal part, which causes the heavy chains to lose the ability to form disulfide bonds with the light chains. The defect in the immunoglobulins presumably arises during somatic hypermutation. Deletion of the N-terminal part of the heavy chain disease protein leads to aggregation and signaling of the B cell receptor, presumably due to the loss of the anti-aggregating properties of the light chain.".
- Heavy_chain_disease diseasesdb "442".
- Heavy_chain_disease emedicineSubject "med".
- Heavy_chain_disease emedicineTopic "958".
- Heavy_chain_disease icd10 "C88.1-C88.2".
- Heavy_chain_disease icd9 "273.2".
- Heavy_chain_disease meshId "D006362".
- Heavy_chain_disease wikiPageID "16031428".
- Heavy_chain_disease wikiPageRevisionID "592331006".
- Heavy_chain_disease diseasesdb "442".
- Heavy_chain_disease emedicinesubj "med".
- Heavy_chain_disease emedicinetopic "958".
- Heavy_chain_disease hasPhotoCollection Heavy_chain_disease.
- Heavy_chain_disease icd "273.2".
- Heavy_chain_disease icd "C88.1-C88.2".
- Heavy_chain_disease meshid "D006362".
- Heavy_chain_disease name "Heavy chain disease".
- Heavy_chain_disease wordnet_type synset-disease-noun-1.
- Heavy_chain_disease subject Category:Immune_system_disorders.
- Heavy_chain_disease type Abstraction100002137.
- Heavy_chain_disease type Attribute100024264.
- Heavy_chain_disease type Condition113920835.
- Heavy_chain_disease type Disease114070360.
- Heavy_chain_disease type Disorder114052403.
- Heavy_chain_disease type IllHealth114052046.
- Heavy_chain_disease type Illness114061805.
- Heavy_chain_disease type ImmuneSystemDisorders.
- Heavy_chain_disease type PathologicalState114051917.
- Heavy_chain_disease type PhysicalCondition114034177.
- Heavy_chain_disease type State100024720.
- Heavy_chain_disease type Disease.
- Heavy_chain_disease type AilmentCondition.
- Heavy_chain_disease type Situation.
- Heavy_chain_disease comment "Heavy chain disease is a form of paraproteinemia with a proliferation of cells producing immunoglobulin heavy chains.This disease is characterized by an excessive production of heavy chains that are short and truncated. These heavy chain disease proteins have various deletions, mainly in their amino-terminal part, which causes the heavy chains to lose the ability to form disulfide bonds with the light chains. The defect in the immunoglobulins presumably arises during somatic hypermutation.".
- Heavy_chain_disease label "Heavy chain disease".
- Heavy_chain_disease label "Malattie delle catene pesanti".
- Heavy_chain_disease label "داء السلسلة الثقيلة".
- Heavy_chain_disease sameAs Malattie_delle_catene_pesanti.
- Heavy_chain_disease sameAs m.03qlc9l.
- Heavy_chain_disease sameAs Q3843813.
- Heavy_chain_disease sameAs Q3843813.
- Heavy_chain_disease sameAs Heavy_chain_disease.
- Heavy_chain_disease wasDerivedFrom Heavy_chain_disease?oldid=592331006.
- Heavy_chain_disease isPrimaryTopicOf Heavy_chain_disease.
- Heavy_chain_disease name "Heavy chain disease".