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- suppressor_ratio abstract "The T-Lymphocyte Helper/Suppressor Profile (Helper/Suppressor ratio, T4:T8 ratio, CD4:CD8 ratio) is a basic laboratory test in which the percentage of CD3-positive lymphocytes in the blood positive for CD4 (T helper cells) and CD8 (a class of regulatory T cells) are counted and compared. Normal values (95% confidence intervals) are approximately 30-60% CD4 and 10-30% CD8 depending on age (ratio 0.9 to 3.7 in adults). One reason for abnormal results is the loss of CD4-positive cells to the Human Immunodeficiency Virus [HIV] infection.The loss of CD4-positive cells to HIV infection can result in various distortions in the ratio, as in the initial period, production of HIV specific CD8 positive cells will cause a large fall in the ratio, but subsequent immunosuppression over time may lead to overall non production of immune cells and inversion of the ratio. It has been shown that the degree of inversion of this ratio in individuals on antiretroviral therapy is indicative of the age of the infection and independently predictive of mortality associated with non HIV events.".
- suppressor_ratio wikiPageID "12846099".
- suppressor_ratio wikiPageRevisionID "590869691".
- suppressor_ratio hasPhotoCollection suppressor_ratio.
- suppressor_ratio subject Category:Blood_tests.
- suppressor_ratio type Abstraction100002137.
- suppressor_ratio type Act100030358.
- suppressor_ratio type Activity100407535.
- suppressor_ratio type Assay100791527.
- suppressor_ratio type Attempt100786195.
- suppressor_ratio type Biopsy105740929.
- suppressor_ratio type BloodTest105742551.
- suppressor_ratio type BloodTests.
- suppressor_ratio type DiagnosticTest105739043.
- suppressor_ratio type Event100029378.
- suppressor_ratio type PsychologicalFeature100023100.
- suppressor_ratio type Test100791078.
- suppressor_ratio type YagoPermanentlyLocatedEntity.
- suppressor_ratio comment "The T-Lymphocyte Helper/Suppressor Profile (Helper/Suppressor ratio, T4:T8 ratio, CD4:CD8 ratio) is a basic laboratory test in which the percentage of CD3-positive lymphocytes in the blood positive for CD4 (T helper cells) and CD8 (a class of regulatory T cells) are counted and compared. Normal values (95% confidence intervals) are approximately 30-60% CD4 and 10-30% CD8 depending on age (ratio 0.9 to 3.7 in adults).".
- suppressor_ratio label "Helper/suppressor ratio".
- suppressor_ratio sameAs m.0ggcb6.
- suppressor_ratio sameAs Q5710202.
- suppressor_ratio sameAs Q5710202.
- suppressor_ratio sameAs suppressor_ratio.
- suppressor_ratio wasDerivedFrom suppressor_ratio?oldid=590869691.
- suppressor_ratio isPrimaryTopicOf suppressor_ratio.