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- Hematopoietic_stem_cell abstract "Hematopoietic stem cells (HSCs) are the blood cells that give rise to all the other blood cells and are derived from mesoderm.They give rise to the myeloid (monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells), and lymphoid lineages (T-cells, B-cells, NK-cells). The definition of hematopoietic stem cells has changed in the last two decades. The hematopoietic tissue contains cells with long-term and short-term regeneration capacities and committed multipotent, oligopotent, and unipotent progenitors. HSCs constitute 1:10.000 of cells in myeloid tissue.HSCs are a heterogeneous population. Three classes of stem cells exist, distinguished by their ratio of lymphoid to myeloid progeny (L/M) in blood. Myeloid-biased (My-bi) HSC have low L/M ratio (>0, <3), whereas lymphoid-biased (Ly-bi) HSC show a large ratio (>10). The third category consists of the balanced (Bala) HSC for which 3 ≤ L/M ≤ 10. Only the myeloid-biased and -balanced HSCs have durable self-renewal properties. In addition, serial transplantation experiments have shown that each subtype preferentially re-creates its blood cell type distribution, suggesting an inherited epigenetic program for each subtype.HSC studies through much of the past half century have led to a much deeper understanding. More recent advances have resulted in the use of HSC transplants in the treatment of cancers and other immune system disorders.".
- Hematopoietic_stem_cell thumbnail Hematopoiesis_simple.svg?width=300.
- Hematopoietic_stem_cell wikiPageExternalLink chapter5.asp.
- Hematopoietic_stem_cell wikiPageExternalLink blood-stem-cells-pioneers-stem-cell-research.
- Hematopoietic_stem_cell wikiPageID "1264088".
- Hematopoietic_stem_cell wikiPageRevisionID "605850692".
- Hematopoietic_stem_cell caption "Overview of normal human hematopoiesis".
- Hematopoietic_stem_cell hasPhotoCollection Hematopoietic_stem_cell.
- Hematopoietic_stem_cell latin "Cellula haematopoietica praecursoria".
- Hematopoietic_stem_cell name "Hematopoietic stem cell".
- Hematopoietic_stem_cell subject Category:Blood_cells.
- Hematopoietic_stem_cell subject Category:Hematopoietic_stem_cells.
- Hematopoietic_stem_cell subject Category:Leukocytes.
- Hematopoietic_stem_cell subject Category:Stem_cells.
- Hematopoietic_stem_cell type BloodCell105449268.
- Hematopoietic_stem_cell type BloodCells.
- Hematopoietic_stem_cell type Cell100006484.
- Hematopoietic_stem_cell type FreePhagocyte105451265.
- Hematopoietic_stem_cell type HematopoieticStemCells.
- Hematopoietic_stem_cell type Leukocyte105449959.
- Hematopoietic_stem_cell type Leukocytes.
- Hematopoietic_stem_cell type LivingThing100004258.
- Hematopoietic_stem_cell type Object100002684.
- Hematopoietic_stem_cell type Phagocyte105450888.
- Hematopoietic_stem_cell type PhysicalEntity100001930.
- Hematopoietic_stem_cell type SomaticCell105430628.
- Hematopoietic_stem_cell type StemCell105607863.
- Hematopoietic_stem_cell type StemCells.
- Hematopoietic_stem_cell type Whole100003553.
- Hematopoietic_stem_cell type AnatomicalStructure.
- Hematopoietic_stem_cell type BiologicalObject.
- Hematopoietic_stem_cell comment "Hematopoietic stem cells (HSCs) are the blood cells that give rise to all the other blood cells and are derived from mesoderm.They give rise to the myeloid (monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells), and lymphoid lineages (T-cells, B-cells, NK-cells). The definition of hematopoietic stem cells has changed in the last two decades.".
- Hematopoietic_stem_cell label "Cellula staminale ematopoietica".
- Hematopoietic_stem_cell label "Cellule souche hématopoïétique".
- Hematopoietic_stem_cell label "Hematopoietic stem cell".
- Hematopoietic_stem_cell label "Hematopoëtische stamcel".
- Hematopoietic_stem_cell label "Hemocitoblasto".
- Hematopoietic_stem_cell label "Hemocitoblasto".
- Hematopoietic_stem_cell label "Hämatopoetische Stammzelle".
- Hematopoietic_stem_cell label "Komórka macierzysta hemopoezy".
- Hematopoietic_stem_cell label "Гемоцитобласт".
- Hematopoietic_stem_cell label "خلية جذعية مكونة للدم".
- Hematopoietic_stem_cell label "造血干细胞".
- Hematopoietic_stem_cell label "造血幹細胞".
- Hematopoietic_stem_cell sameAs Hematopoetická_kmenová_buňka.
- Hematopoietic_stem_cell sameAs Hämatopoetische_Stammzelle.
- Hematopoietic_stem_cell sameAs Hemocitoblasto.
- Hematopoietic_stem_cell sameAs Cellule_souche_hématopoïétique.
- Hematopoietic_stem_cell sameAs Cellula_staminale_ematopoietica.
- Hematopoietic_stem_cell sameAs 造血幹細胞.
- Hematopoietic_stem_cell sameAs 조혈모세포.
- Hematopoietic_stem_cell sameAs Hematopoëtische_stamcel.
- Hematopoietic_stem_cell sameAs Komórka_macierzysta_hemopoezy.
- Hematopoietic_stem_cell sameAs Hemocitoblasto.
- Hematopoietic_stem_cell sameAs m.04nblk.
- Hematopoietic_stem_cell sameAs Q514525.
- Hematopoietic_stem_cell sameAs Q514525.
- Hematopoietic_stem_cell sameAs Hematopoietic_stem_cell.
- Hematopoietic_stem_cell wasDerivedFrom Hematopoietic_stem_cell?oldid=605850692.
- Hematopoietic_stem_cell depiction Hematopoiesis_simple.svg.
- Hematopoietic_stem_cell isPrimaryTopicOf Hematopoietic_stem_cell.
- Hematopoietic_stem_cell name "Hematopoietic stem cell".