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- Heptamethine_dyes abstract "Heptamethine dyes are a subclass of chemical compounds within the indocyanine dye family and are currently being explored for their unique uses in medical diagnostics, the development of theranostics, the individualized treatment of cancerous patients with the aid of PDT, co-administration with other drugs, and irradiation. In tests it is administered intravenously and, depending on hepatic functionality, have been found to be nontoxic at doses of 500 times that needed to fluoresce the tumor cells. The therapeutic properties appear safe and viable due to the light wavelength absorption being just outside of the visible spectrum in the Near Infra-Red range.The characteristics of heptamethine dyes can be understood by comparing research data on different dyes within the family. For example, the IR-780 dye exhibits a peak spectral absorption of around 780 nm depending on the diluting agent. Tests have also identified the viability of other analogs including IR-783 and MHI-148. One specific analog of interest is IR-808 which has shown to exhibit not only similar binding and illumination characteristics of the IR-780 analog, but it has shown to have significant photodependent cytotoxicity in various myeloma cell lines and moderate cytotoxicity in HeLa cells both in vivo and in vitro without the need to conjugate and likely change the conformation ability of co-administered cancer drugs such as paclitaxel.".
- Heptamethine_dyes iupacName "Br 2-[(E)-2-[(3E)-2-chloro-3-\\{2-[(2E)-3,3-dimethyl-1-pentyl-2,3-dihydro-1H-indol-2-ylidene]ethylidene}cyclohex-1-en-1-yl]ethenyl]-3,3-dimethyl-1-pentyl-3H-indol-1-ium".
- Heptamethine_dyes thumbnail Heptamathine_dye_IR-808.png?width=300.
- Heptamethine_dyes wikiPageExternalLink intrace-medical.com.
- Heptamethine_dyes wikiPageExternalLink www.cyandye.us.
- Heptamethine_dyes wikiPageExternalLink Near-Infrared-Dyes-c92.htm?gclid=CKjwmPD7l68CFQaFhwodNVcqzw.
- Heptamethine_dyes wikiPageExternalLink irdye.
- Heptamethine_dyes wikiPageExternalLink catalog.
- Heptamethine_dyes wikiPageExternalLink If-Its-Breast-Cancer.
- Heptamethine_dyes wikiPageExternalLink heptamethine.
- Heptamethine_dyes wikiPageID "35304185".
- Heptamethine_dyes wikiPageRevisionID "602730317".
- Heptamethine_dyes author "Trifectaus".
- Heptamethine_dyes date "2012-04-01".
- Heptamethine_dyes description "Molecular structure of heptamethine dye".
- Heptamethine_dyes hasPhotoCollection Heptamethine_dyes.
- Heptamethine_dyes imagefile "Heptamathine dye IR-808.png".
- Heptamethine_dyes imagesize "200".
- Heptamethine_dyes iupacname "Br 2-[-2-[-2-chloro-3-\\{2-[-3,3-dimethyl-1-pentyl-2,3-dihydro-1H-indol-2-ylidene]ethylidene}cyclohex-1-en-1-yl]ethenyl]-3,3-dimethyl-1-pentyl-3H-indol-1-ium".
- Heptamethine_dyes name "IR-808, A heptamethine dye".
- Heptamethine_dyes othernames "Otterblue".
- Heptamethine_dyes source "using marvinsketch".
- Heptamethine_dyes subject Category:Dyes.
- Heptamethine_dyes subject Category:Fluorescence.
- Heptamethine_dyes subject Category:Fluorescent_dyes.
- Heptamethine_dyes subject Category:Phosphors_and_scintillators.
- Heptamethine_dyes type AbsorptionIndicator114598383.
- Heptamethine_dyes type Abstraction100002137.
- Heptamethine_dyes type Chemical114806838.
- Heptamethine_dyes type ColoringMaterial114984973.
- Heptamethine_dyes type Compound114818238.
- Heptamethine_dyes type Dye114985383.
- Heptamethine_dyes type Dyes.
- Heptamethine_dyes type Fluorescein114987695.
- Heptamethine_dyes type FluorescentDyes.
- Heptamethine_dyes type Indicator114917208.
- Heptamethine_dyes type Material114580897.
- Heptamethine_dyes type Matter100020827.
- Heptamethine_dyes type Part113809207.
- Heptamethine_dyes type Phosphor114649036.
- Heptamethine_dyes type PhosphorsAndScintillators.
- Heptamethine_dyes type PhysicalEntity100001930.
- Heptamethine_dyes type Relation100031921.
- Heptamethine_dyes type Substance100019613.
- Heptamethine_dyes type Synthetic114901959.
- Heptamethine_dyes type ChemicalCompound.
- Heptamethine_dyes type ChemicalSubstance.
- Heptamethine_dyes type ChemicalObject.
- Heptamethine_dyes type Thing.
- Heptamethine_dyes comment "Heptamethine dyes are a subclass of chemical compounds within the indocyanine dye family and are currently being explored for their unique uses in medical diagnostics, the development of theranostics, the individualized treatment of cancerous patients with the aid of PDT, co-administration with other drugs, and irradiation.".
- Heptamethine_dyes label "Heptamethine dyes".
- Heptamethine_dyes sameAs m.0j7lj0l.
- Heptamethine_dyes sameAs Q5732050.
- Heptamethine_dyes sameAs Q5732050.
- Heptamethine_dyes sameAs Heptamethine_dyes.
- Heptamethine_dyes wasDerivedFrom Heptamethine_dyes?oldid=602730317.
- Heptamethine_dyes depiction Heptamathine_dye_IR-808.png.
- Heptamethine_dyes isPrimaryTopicOf Heptamethine_dyes.
- Heptamethine_dyes name "IR-808, A heptamethine dye".