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- HgcC_family_RNA abstract "HgcC is a small non coding RNA (ncRNA). It is the functional product of a gene which is not translated into protein.This ncRNA gene was originally identified by computationally searching the genome of the thermophilic archea Methanococcus jannaschii for non-coding regions of high guanine-cytosine (GC) content. The original rational for this search was based on the observation that the genomes of these bacteria are adenosine-thiamine (AT) rich and consequently have a low GC content. However, the GC content of ribosomal RNA (rRNA) and transfer RNA (tRNA) genes in hyperthermophiles shows a strong correlation with optimal growth temperature. It was proposed that non coding regions of high GC-content might encode functional RNA products. The computational screen identified a number of novel ncRNA genes in the genome of M.jannaschii. These were named hgc- ("high GC") A, B, C, D, E, F and G. Two other homologues were detected called HhcA and HhcB after "homologue of hgcC". A further RNA element, SscA RNA, was also identified.The HgcC gene product was experimentally validated by Northern blot and RACE-PCR analysis. The function of this ncRNA is not known.".
- HgcC_family_RNA thumbnail RF00062.jpg?width=300.
- HgcC_family_RNA wikiPageID "11420931".
- HgcC_family_RNA wikiPageRevisionID "471776923".
- HgcC_family_RNA caption "Predicted secondary structure and sequence conservation of HgcC".
- HgcC_family_RNA hasPhotoCollection HgcC_family_RNA.
- HgcC_family_RNA id "RF00062".
- HgcC_family_RNA name "HgcC family RNA".
- HgcC_family_RNA rfam "RF00062".
- HgcC_family_RNA rnaType Gene.
- HgcC_family_RNA symbol "HgcC".
- HgcC_family_RNA taxDomain Archaea.
- HgcC_family_RNA subject Category:Non-coding_RNA.
- HgcC_family_RNA comment "HgcC is a small non coding RNA (ncRNA). It is the functional product of a gene which is not translated into protein.This ncRNA gene was originally identified by computationally searching the genome of the thermophilic archea Methanococcus jannaschii for non-coding regions of high guanine-cytosine (GC) content. The original rational for this search was based on the observation that the genomes of these bacteria are adenosine-thiamine (AT) rich and consequently have a low GC content.".
- HgcC_family_RNA label "HgcC family RNA".
- HgcC_family_RNA sameAs m.02rbyc2.
- HgcC_family_RNA sameAs Q5750085.
- HgcC_family_RNA sameAs Q5750085.
- HgcC_family_RNA wasDerivedFrom HgcC_family_RNA?oldid=471776923.
- HgcC_family_RNA depiction RF00062.jpg.
- HgcC_family_RNA isPrimaryTopicOf HgcC_family_RNA.