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- Homeodomain_fold abstract "The homeodomain fold is a protein structural domain that binds DNA or RNA and is thus commonly found in transcription factors. The fold consists of a 60-amino acid helix-turn-helix structure in which three alpha helices are connected by short loop regions. The N-terminal two helices are antiparallel and the longer C-terminal helix is roughly perpendicular to the axes established by the first two. It is this third helix that interacts directly with DNA. Homeodomain folds are found exclusively in eukaryotes but have high homology to lambda phage proteins that alter the expression of genes in prokaryotes. Many homeodomains induce cellular differentiation by initiating the cascades of coregulated genes required to produce individual tissues and organs, while homeodomain proteins like NANOG are involved in maintaining pluripotency.".
- Homeodomain_fold symbol "Homeobox".
- Homeodomain_fold thumbnail Homeodomain-dna-1ahd.png?width=300.
- Homeodomain_fold wikiPageExternalLink consensus.gif.
- Homeodomain_fold wikiPageID "6221726".
- Homeodomain_fold wikiPageRevisionID "592766076".
- Homeodomain_fold caption "The Antennapedia homeodomain protein from Drosophila melanogaster bound to a fragment of DNA. The recognition helix and unstructured N-terminus are bound in the major and minor grooves respectively.".
- Homeodomain_fold hasPhotoCollection Homeodomain_fold.
- Homeodomain_fold interpro "IPR001356".
- Homeodomain_fold name "Homeobox domain".
- Homeodomain_fold pdb ", , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,".
- Homeodomain_fold pfam "PF00046".
- Homeodomain_fold pfamClan "CL0123".
- Homeodomain_fold prosite "PS50071".
- Homeodomain_fold scop "1".
- Homeodomain_fold smart "SM00389".
- Homeodomain_fold symbol "Homeobox".
- Homeodomain_fold subject Category:Protein_domains.
- Homeodomain_fold subject Category:Protein_folds.
- Homeodomain_fold subject Category:Transcription_factors.
- Homeodomain_fold type Abstraction100002137.
- Homeodomain_fold type AngularShape113864763.
- Homeodomain_fold type Attribute100024264.
- Homeodomain_fold type Beginning107290905.
- Homeodomain_fold type Cause107326557.
- Homeodomain_fold type Environment113934596.
- Homeodomain_fold type Event100029378.
- Homeodomain_fold type Factor107327805.
- Homeodomain_fold type Fold113907415.
- Homeodomain_fold type Happening107283608.
- Homeodomain_fold type Origin107323922.
- Homeodomain_fold type ProteinDomains.
- Homeodomain_fold type ProteinFolds.
- Homeodomain_fold type PsychologicalFeature100023100.
- Homeodomain_fold type Shape100027807.
- Homeodomain_fold type Situation113927383.
- Homeodomain_fold type Sphere114514039.
- Homeodomain_fold type State100024720.
- Homeodomain_fold type TranscriptionFactors.
- Homeodomain_fold type YagoPermanentlyLocatedEntity.
- Homeodomain_fold type Biomolecule.
- Homeodomain_fold type Protein.
- Homeodomain_fold type BiologicalObject.
- Homeodomain_fold comment "The homeodomain fold is a protein structural domain that binds DNA or RNA and is thus commonly found in transcription factors. The fold consists of a 60-amino acid helix-turn-helix structure in which three alpha helices are connected by short loop regions. The N-terminal two helices are antiparallel and the longer C-terminal helix is roughly perpendicular to the axes established by the first two. It is this third helix that interacts directly with DNA.".
- Homeodomain_fold label "Homeodomain fold".
- Homeodomain_fold label "Homeodominio".
- Homeodomain_fold label "Гомеодомен".
- Homeodomain_fold label "ホメオドメインフォールド".
- Homeodomain_fold sameAs Homeodoména.
- Homeodomain_fold sameAs Homeodominio.
- Homeodomain_fold sameAs ホメオドメインフォールド.
- Homeodomain_fold sameAs m.0fxjpj.
- Homeodomain_fold sameAs Q2658503.
- Homeodomain_fold sameAs Q2658503.
- Homeodomain_fold sameAs Homeodomain_fold.
- Homeodomain_fold wasDerivedFrom Homeodomain_fold?oldid=592766076.
- Homeodomain_fold depiction Homeodomain-dna-1ahd.png.
- Homeodomain_fold isPrimaryTopicOf Homeodomain_fold.