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- Horizon_Discovery abstract "Horizon Discovery Group plc is a UK biotechnology company based in Cambridge founded in 2005 that provides products and services to support research into personalized medicine.The company engages in research into human genetic profiles in health and disease as well as the development of targeted therapeutics, with an emphasis on oncology. Using various genome editing technologies, the company modifies the DNA of various cell lines to mimic genetic defects found in the general population which put people at risk of developing specific cancer types, or that predispose them to benefit from a certain cancer treatment. The company supplies products and services hundreds of biotechnology, diagnostic and pharmaceutical companies, and academic research institutes.In September 2013 Horizon announced 2 major collaborations with Sigma-Aldrich and Harvard University, incorporating the companies' respective nuclease genome-editing technologies into Horizon's GENESIS platform. The first collaboration with Sigma-Aldrich saw the licensing of Zinc Finger Nuclease (ZFN) technology, which provides rapid and efficient knock-out of two or more alleles, complementing the precision of Horizon's proprietary rAAV technology. In the collaboration with Harvard University, Horizon licensed the IP for RNA-guided gene editing system CRISPR, which allows the introduction of a single stranded nick in the genome of mammalian cells, allowing specific specific gene mutations to be created that are not possible with other nuclease technologies.In 2014, Horizon entered into a genetic diagnostic test development collaboration with Transgenomic in which Horizon Diagnostic's quantitative molecular reference standards would be used in all existing and future assays developed.".
- Horizon_Discovery foundingYear "2005".
- Horizon_Discovery industry Biotechnology.
- Horizon_Discovery location Cambridge.
- Horizon_Discovery location United_Kingdom.
- Horizon_Discovery numberOfEmployees "80".
- Horizon_Discovery type Public_limited_company.
- Horizon_Discovery wikiPageExternalLink www.horizondiscovery.com.
- Horizon_Discovery wikiPageExternalLink www.horizondiscovery.com.
- Horizon_Discovery wikiPageExternalLink Contact.
- Horizon_Discovery wikiPageExternalLink www.horizondx.com.
- Horizon_Discovery wikiPageID "41602531".
- Horizon_Discovery wikiPageRevisionID "603017256".
- Horizon_Discovery areaServed "Worldwide".
- Horizon_Discovery founder "Prof. Alberto Bardelli, Dr. Chris Torrance".
- Horizon_Discovery industry Biotechnology.
- Horizon_Discovery keyPeople "Darrin Disley , Ian Gilham".
- Horizon_Discovery location Cambridge.
- Horizon_Discovery location United_Kingdom.
- Horizon_Discovery logo "210".
- Horizon_Discovery name "Horizon Discovery Group plc".
- Horizon_Discovery numEmployees "80".
- Horizon_Discovery type Public_limited_company.
- Horizon_Discovery subject Category:Biotechnology_companies_of_the_United_Kingdom.
- Horizon_Discovery subject Category:Research_support_companies.
- Horizon_Discovery type Agent.
- Horizon_Discovery type Company.
- Horizon_Discovery type Organisation.
- Horizon_Discovery type Organization.
- Horizon_Discovery type Agent.
- Horizon_Discovery type SocialPerson.
- Horizon_Discovery type Thing.
- Horizon_Discovery comment "Horizon Discovery Group plc is a UK biotechnology company based in Cambridge founded in 2005 that provides products and services to support research into personalized medicine.The company engages in research into human genetic profiles in health and disease as well as the development of targeted therapeutics, with an emphasis on oncology.".
- Horizon_Discovery label "Horizon Discovery".
- Horizon_Discovery sameAs m.0zbsl3l.
- Horizon_Discovery sameAs Q16984856.
- Horizon_Discovery sameAs Q16984856.
- Horizon_Discovery wasDerivedFrom Horizon_Discovery?oldid=603017256.
- Horizon_Discovery homepage www.horizondiscovery.com.
- Horizon_Discovery isPrimaryTopicOf Horizon_Discovery.
- Horizon_Discovery name "Horizon Discovery Group plc".