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- Humanized_antibody abstract "Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants produced naturally in humans. The process of "humanization" is usually applied to monoclonal antibodies developed for administration to humans (for example, antibodies developed as anti-cancer drugs). Humanization can be necessary when the process of developing a specific antibody involves generation in a non-human immune system (such as that in mice). The protein sequences of antibodies produced in this way are partially distinct from homologous antibodies occurring naturally in humans, and are therefore potentially immunogenic when administered to human patients (see also Human anti-mouse antibody). Not all monoclonal antibodies designed for human administration need be humanized since many therapies are short-term interventions (see List of monoclonal antibodies to get an overview of the various types of antibodies developed for therapeutic administration in humans). The International Nonproprietary Names of humanized antibodies end in -zumab, as in omalizumab (see Nomenclature of monoclonal antibodies).Humanized antibodies are distinct from chimeric antibodies. The latter also have their protein sequences made more similar to human antibodies, but carry a larger stretch of non-human protein.".
- Humanized_antibody thumbnail Chimeric_and_humanized_antibodies.svg?width=300.
- Humanized_antibody wikiPageID "4414916".
- Humanized_antibody wikiPageRevisionID "591734315".
- Humanized_antibody hasPhotoCollection Humanized_antibody.
- Humanized_antibody subject Category:Monoclonal_antibodies.
- Humanized_antibody type Abstraction100002137.
- Humanized_antibody type Antibody115027189.
- Humanized_antibody type Chemical114806838.
- Humanized_antibody type Compound114818238.
- Humanized_antibody type Macromolecule114944888.
- Humanized_antibody type Material114580897.
- Humanized_antibody type Matter100020827.
- Humanized_antibody type Molecule114682133.
- Humanized_antibody type MonoclonalAntibodies.
- Humanized_antibody type MonoclonalAntibody115029781.
- Humanized_antibody type OrganicCompound114727670.
- Humanized_antibody type Part113809207.
- Humanized_antibody type PhysicalEntity100001930.
- Humanized_antibody type Protein114728724.
- Humanized_antibody type Relation100031921.
- Humanized_antibody type Substance100019613.
- Humanized_antibody type Thing100002452.
- Humanized_antibody type Unit109465459.
- Humanized_antibody comment "Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants produced naturally in humans. The process of "humanization" is usually applied to monoclonal antibodies developed for administration to humans (for example, antibodies developed as anti-cancer drugs).".
- Humanized_antibody label "Humanized antibody".
- Humanized_antibody sameAs m.02p858b.
- Humanized_antibody sameAs Q5939625.
- Humanized_antibody sameAs Q5939625.
- Humanized_antibody sameAs Humanized_antibody.
- Humanized_antibody wasDerivedFrom Humanized_antibody?oldid=591734315.
- Humanized_antibody depiction Chimeric_and_humanized_antibodies.svg.
- Humanized_antibody isPrimaryTopicOf Humanized_antibody.