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- Hypericin abstract "Hypericin is a naphthodianthrone, a red-colored anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.It was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme. The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors. This points in the direction that other constituents are responsible for the MAOI effect. The current belief is that the mechanism of antidepressant activity is due to the inhibition of reuptake of certain neurotransmitters.The large chromophore system in the molecule means that it can cause photosensitivity when ingested beyond threshold amounts.[citation needed] Photosensitivity is often seen in animals that have been allowed to graze on St. John's Wort. Because hypericin accumulates preferentially in cancerous tissues, it is also used as an indicator of cancerous cells. In addition, hypericin is under research as an agent in photodynamic therapy, whereby a biochemical is absorbed by an organism to be later activated with spectrum-specific light from specialized lamps or laser sources, for therapeutic purposes. The antibacterial and antiviral effects of hypericin are also believed to arise from its ability for photo-oxidation of cells and viral particles.Hypericin derives from polyketides cyclisation.".
- Hypericin iupacName "1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione".
- Hypericin thumbnail Hypericin2DACS.svg?width=300.
- Hypericin wikiPageID "850783".
- Hypericin wikiPageRevisionID "595738415".
- Hypericin hasPhotoCollection Hypericin.
- Hypericin imagefile "Hypericin2DACS.svg".
- Hypericin imagefile "Hypericin3Dan.gif".
- Hypericin imagesize "200".
- Hypericin imagesize "220".
- Hypericin iupacname "1346813".
- Hypericin othernames "4574".
- Hypericin verifiedrevid "443864519".
- Hypericin subject Category:Natural_phenols.
- Hypericin subject Category:Virucides.
- Hypericin type Abstraction100002137.
- Hypericin type Chemical114806838.
- Hypericin type Compound114818238.
- Hypericin type Material114580897.
- Hypericin type Matter100020827.
- Hypericin type NaturalPhenols.
- Hypericin type OrganicCompound114727670.
- Hypericin type Part113809207.
- Hypericin type Phenol114989545.
- Hypericin type PhysicalEntity100001930.
- Hypericin type Relation100031921.
- Hypericin type Substance100019613.
- Hypericin type ChemicalCompound.
- Hypericin type ChemicalSubstance.
- Hypericin type ChemicalSubstanceType.
- Hypericin type ChemicalObject.
- Hypericin type Thing.
- Hypericin comment "Hypericin is a naphthodianthrone, a red-colored anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor.".
- Hypericin label "Hipericina".
- Hypericin label "Hypericin".
- Hypericin label "Hypericin".
- Hypericin label "Гиперицин".
- Hypericin label "ヒペリシン".
- Hypericin sameAs Hypericin.
- Hypericin sameAs Hipericina.
- Hypericin sameAs ヒペリシン.
- Hypericin sameAs m.03h24b.
- Hypericin sameAs Q425409.
- Hypericin sameAs Q425409.
- Hypericin sameAs Hypericin.
- Hypericin wasDerivedFrom Hypericin?oldid=595738415.
- Hypericin depiction Hypericin2DACS.svg.
- Hypericin isPrimaryTopicOf Hypericin.