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- Imidazenil abstract "Imidazenil is an anxiolytic drug which is derived from the benzodiazepine family, and is most closely related to other imidazobenzodiazepines such as midazolam, flumazenil and bretazenil.Imidazenil is a GABAA partial agonist with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative or amnestic effects. In fact, imidazenil blocks the sedative effects of diazepam, yet without lowering the convulsion threshold, and so potentially could be a more flexible antidote than the antagonist flumazenil which is commonly used to treat benzodiazepine overdose at present. This unusual profile of effects makes imidazenil potentially a very useful drug. In animal studies it has been shown to be an effective anxiolytic and strong anticonvulsant, yet without many of the side effects associated with other benzodiazepines; it does not produce tolerance or dependence, reverses the amnestic effects of conventional benzodiazepines, and does not potentiate the effects of alcohol.Imidazenil has not yet been developed commercially for use in humans, however it has been suggested as a safe and effective treatment for anxiety, a potent yet non-sedating anticonvulsant which might be particularly useful in the treatment of poisoning with organophosphate nerve agents, and as a novel treatment for schizophrenia.".
- Imidazenil atcPrefix "none".
- Imidazenil casNumber "151271-08-8".
- Imidazenil iupacName "6-(2-bromophenyl)-8-fluoro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide".
- Imidazenil pubchem "119194".
- Imidazenil thumbnail Imidazenil_structure.svg?width=300.
- Imidazenil wikiPageID "13351850".
- Imidazenil wikiPageRevisionID "565346603".
- Imidazenil atcPrefix "none".
- Imidazenil br "1".
- Imidazenil c "18".
- Imidazenil casNumber "151271".
- Imidazenil chemspiderid "106482".
- Imidazenil f "1".
- Imidazenil h "12".
- Imidazenil hasPhotoCollection Imidazenil.
- Imidazenil inchi "1".
- Imidazenil inchikey "OCJHYHKWUWSHEN-UHFFFAOYAC".
- Imidazenil iupacName "6".
- Imidazenil molecularWeight "399.216".
- Imidazenil n "4".
- Imidazenil o "1".
- Imidazenil pubchem "119194".
- Imidazenil smiles "Brc4ccccc4C/2=N/Cc1cCN".
- Imidazenil stdinchi "1".
- Imidazenil stdinchikey "OCJHYHKWUWSHEN-UHFFFAOYSA-N".
- Imidazenil verifiedrevid "447928757".
- Imidazenil width "170".
- Imidazenil subject Category:Amides.
- Imidazenil subject Category:Imidazobenzodiazepines.
- Imidazenil subject Category:Organobromides.
- Imidazenil subject Category:Organofluorides.
- Imidazenil type Abstraction100002137.
- Imidazenil type Amide114724264.
- Imidazenil type Amides.
- Imidazenil type Chemical114806838.
- Imidazenil type Compound114818238.
- Imidazenil type Material114580897.
- Imidazenil type Matter100020827.
- Imidazenil type OrganicCompound114727670.
- Imidazenil type Part113809207.
- Imidazenil type PhysicalEntity100001930.
- Imidazenil type Relation100031921.
- Imidazenil type Substance100019613.
- Imidazenil type Drug.
- Imidazenil type DrugProduct.
- Imidazenil type FunctionalSubstance.
- Imidazenil comment "Imidazenil is an anxiolytic drug which is derived from the benzodiazepine family, and is most closely related to other imidazobenzodiazepines such as midazolam, flumazenil and bretazenil.Imidazenil is a GABAA partial agonist with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative or amnestic effects.".
- Imidazenil label "Imidazenil".
- Imidazenil sameAs m.03c2kl6.
- Imidazenil sameAs Q15409429.
- Imidazenil sameAs Q15409429.
- Imidazenil sameAs Imidazenil.
- Imidazenil wasDerivedFrom Imidazenil?oldid=565346603.
- Imidazenil depiction Imidazenil_structure.svg.
- Imidazenil isPrimaryTopicOf Imidazenil.