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- Immortal_DNA_strand_hypothesis abstract "The immortal DNA strand hypothesis was proposed in 1975 by John Cairns as a mechanism for adult stem cells to minimize mutations in their genomes. This hypothesis proposes that instead of segregating their DNA during mitosis in a random manner, adult stem cells divide their DNA asymmetrically, and retain a distinct template set of DNA strands (parental strands) in each division. By retaining the same set of template DNA strands, adult stem cells would pass mutations arising from errors in DNA replication on to non-stem cell daughters that soon terminally differentiate (end mitotic divisions and become a functional cell). Passing on these replication errors would allow adult stem cells to reduce their rate of accumulation of mutations that could lead to serious genetic disorders such as cancer.Although evidence for this mechanism exists, whether it is a mechanism acting in adult stem cells in vivo is still controversial.".
- Immortal_DNA_strand_hypothesis wikiPageExternalLink 1045b.
- Immortal_DNA_strand_hypothesis wikiPageExternalLink 46.
- Immortal_DNA_strand_hypothesis wikiPageExternalLink 1045c.
- Immortal_DNA_strand_hypothesis wikiPageID "7188879".
- Immortal_DNA_strand_hypothesis wikiPageRevisionID "594122396".
- Immortal_DNA_strand_hypothesis hasPhotoCollection Immortal_DNA_strand_hypothesis.
- Immortal_DNA_strand_hypothesis subject Category:Cell_biology.
- Immortal_DNA_strand_hypothesis subject Category:DNA.
- Immortal_DNA_strand_hypothesis subject Category:Developmental_biology.
- Immortal_DNA_strand_hypothesis subject Category:Stem_cells.
- Immortal_DNA_strand_hypothesis type Cell100006484.
- Immortal_DNA_strand_hypothesis type LivingThing100004258.
- Immortal_DNA_strand_hypothesis type Object100002684.
- Immortal_DNA_strand_hypothesis type PhysicalEntity100001930.
- Immortal_DNA_strand_hypothesis type SomaticCell105430628.
- Immortal_DNA_strand_hypothesis type StemCell105607863.
- Immortal_DNA_strand_hypothesis type StemCells.
- Immortal_DNA_strand_hypothesis type Whole100003553.
- Immortal_DNA_strand_hypothesis comment "The immortal DNA strand hypothesis was proposed in 1975 by John Cairns as a mechanism for adult stem cells to minimize mutations in their genomes. This hypothesis proposes that instead of segregating their DNA during mitosis in a random manner, adult stem cells divide their DNA asymmetrically, and retain a distinct template set of DNA strands (parental strands) in each division.".
- Immortal_DNA_strand_hypothesis label "Immortal DNA strand hypothesis".
- Immortal_DNA_strand_hypothesis label "Théorie de l'ADN immortel".
- Immortal_DNA_strand_hypothesis sameAs Théorie_de_l'ADN_immortel.
- Immortal_DNA_strand_hypothesis sameAs m.025vkvn.
- Immortal_DNA_strand_hypothesis sameAs Q2892307.
- Immortal_DNA_strand_hypothesis sameAs Q2892307.
- Immortal_DNA_strand_hypothesis sameAs Immortal_DNA_strand_hypothesis.
- Immortal_DNA_strand_hypothesis wasDerivedFrom Immortal_DNA_strand_hypothesis?oldid=594122396.
- Immortal_DNA_strand_hypothesis isPrimaryTopicOf Immortal_DNA_strand_hypothesis.