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- Itolizumab abstract "Itolizumab (INN, trade name Alzumab) is a ‘first in class’ humanized IgG1 monoclonal antibody developed by Biocon. It selectively targets CD6, a pan T cell marker involved in co-stimulation, adhesion and maturation of T cells. Itolizumab, by binding to CD6, down regulates T cell activation, causes reduction in synthesis of pro-inflammatory cytokines and possibly plays an important role by reducing T cell infiltration at sites of inflammation. A double blind, placebo controlled, phase III treat –Plaq study of itolizumab successfully met the pre-specified primary end-point of significant improvement in PASI-75 (Psoriasis Area and Severity Index) score after 12 weeks of treatment in patients with moderate to severe psoriasis compared to placebo. Biocon received marketing authorization for the drug from the Drugs Controller General of India (DCGI) in January 2013 and marketing within India commenced in August 2013.".
- Itolizumab atcPrefix "none".
- Itolizumab casNumber "1116433-11-4".
- Itolizumab fdaUniiCode "XQQ2RHV14N".
- Itolizumab wikiPageID "33052137".
- Itolizumab wikiPageRevisionID "602018034".
- Itolizumab atcPrefix "none".
- Itolizumab casNumber "1116433".
- Itolizumab chemspiderid "NA".
- Itolizumab hasPhotoCollection Itolizumab.
- Itolizumab legalStatus "Approved in India".
- Itolizumab mabType "mab".
- Itolizumab source "zu".
- Itolizumab target CD6.
- Itolizumab tradename "Alzumab".
- Itolizumab type "mab".
- Itolizumab unii "XQQ2RHV14N".
- Itolizumab verifiedfields "changed".
- Itolizumab verifiedrevid "458270653".
- Itolizumab subject Category:Monoclonal_antibodies.
- Itolizumab type Abstraction100002137.
- Itolizumab type Antibody115027189.
- Itolizumab type Chemical114806838.
- Itolizumab type Compound114818238.
- Itolizumab type Macromolecule114944888.
- Itolizumab type Material114580897.
- Itolizumab type Matter100020827.
- Itolizumab type Molecule114682133.
- Itolizumab type MonoclonalAntibodies.
- Itolizumab type MonoclonalAntibody115029781.
- Itolizumab type OrganicCompound114727670.
- Itolizumab type Part113809207.
- Itolizumab type PhysicalEntity100001930.
- Itolizumab type Protein114728724.
- Itolizumab type Relation100031921.
- Itolizumab type Substance100019613.
- Itolizumab type Thing100002452.
- Itolizumab type Unit109465459.
- Itolizumab type Drug.
- Itolizumab type FunctionalSubstance.
- Itolizumab comment "Itolizumab (INN, trade name Alzumab) is a ‘first in class’ humanized IgG1 monoclonal antibody developed by Biocon. It selectively targets CD6, a pan T cell marker involved in co-stimulation, adhesion and maturation of T cells. Itolizumab, by binding to CD6, down regulates T cell activation, causes reduction in synthesis of pro-inflammatory cytokines and possibly plays an important role by reducing T cell infiltration at sites of inflammation.".
- Itolizumab label "Itolizumab".
- Itolizumab label "إيتوليزوماب".
- Itolizumab sameAs m.0h551rm.
- Itolizumab sameAs Q6094826.
- Itolizumab sameAs Q6094826.
- Itolizumab sameAs Itolizumab.
- Itolizumab wasDerivedFrom Itolizumab?oldid=602018034.
- Itolizumab isPrimaryTopicOf Itolizumab.