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- Jaffe_reaction abstract "The Jaffe reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. In 1886, Max Jaffe (1841–1911) wrote about its basic principles in the paper Über den Niederschlag, welchen Pikrinsäre in normalem Harn erzeugt und über eine neue Reaction des Kreatinins in which he described the properties of creatinine and picric acid in an alkaline solution. The color change that occurred was directly proportional to the concentration of creatinine, however he also noted that several other organic compounds induced similar reactions. In the early 20th century, Otto Folin adapted Jaffe's research into a clinical procedure. The Jaffe reaction, despite its nonspecificity for creatinine, is still widely employed as the method of choice for creatinine testing due to its speed, adaptability in automated analysis, and cost-effectiveness, and is the oldest methodology continued to be used in the medical laboratory. It is this nonspecificity that has motivated the development of new reference methods for creatinine analysis into the 21st century.".
- Jaffe_reaction almaMater Humboldt_University_of_Berlin.
- Jaffe_reaction birthDate "1841-07-25".
- Jaffe_reaction birthPlace Silesia.
- Jaffe_reaction birthYear "1841".
- Jaffe_reaction deathDate "1911-10-26".
- Jaffe_reaction deathPlace Berlin.
- Jaffe_reaction deathPlace Germany.
- Jaffe_reaction deathYear "1911".
- Jaffe_reaction field Biochemistry.
- Jaffe_reaction field Pathology.
- Jaffe_reaction field Pharmacology.
- Jaffe_reaction knownFor Creatinine.
- Jaffe_reaction knownFor Picric_acid.
- Jaffe_reaction thumbnail Max_Jaffe.jpg?width=300.
- Jaffe_reaction wikiPageExternalLink reader?id=lo4WAAAAIAAJ&lr=&printsec=frontcover&output=reader&pg=GBS.PA81.
- Jaffe_reaction wikiPageExternalLink lit16635?.
- Jaffe_reaction wikiPageExternalLink 5.full.pdf.
- Jaffe_reaction wikiPageExternalLink 469.full.pdf.
- Jaffe_reaction wikiPageID "37425225".
- Jaffe_reaction wikiPageRevisionID "603030096".
- Jaffe_reaction almaMater Humboldt_University_of_Berlin.
- Jaffe_reaction birthDate "1841-07-25".
- Jaffe_reaction birthPlace "Grünberg, Silesia".
- Jaffe_reaction dateOfBirth "1841-07-25".
- Jaffe_reaction dateOfDeath "1911-10-26".
- Jaffe_reaction deathDate "1911-10-26".
- Jaffe_reaction deathPlace Berlin.
- Jaffe_reaction deathPlace Germany.
- Jaffe_reaction field Biochemistry.
- Jaffe_reaction field Pathology.
- Jaffe_reaction field Pharmacology.
- Jaffe_reaction hasPhotoCollection Jaffe_reaction.
- Jaffe_reaction imageSize "200".
- Jaffe_reaction knownFor "Jaffe reaction of creatinine and picric acid—the oldest clinical methodology still in use.".
- Jaffe_reaction name "Max Jaffe".
- Jaffe_reaction name "reaction, Jaffe".
- Jaffe_reaction nationality "German".
- Jaffe_reaction placeOfBirth "Grünberg, Silesia".
- Jaffe_reaction placeOfDeath Berlin.
- Jaffe_reaction placeOfDeath Germany.
- Jaffe_reaction shortDescription "German biochemist".
- Jaffe_reaction workInstitutions University_of_Königsberg.
- Jaffe_reaction description "German biochemist".
- Jaffe_reaction description "German biochemist".
- Jaffe_reaction subject Category:Biochemistry_methods.
- Jaffe_reaction subject Category:Biochemists.
- Jaffe_reaction subject Category:Name_reactions.
- Jaffe_reaction type Agent.
- Jaffe_reaction type Person.
- Jaffe_reaction type Scientist.
- Jaffe_reaction type Person.
- Jaffe_reaction type Q215627.
- Jaffe_reaction type Q5.
- Jaffe_reaction type Agent.
- Jaffe_reaction type NaturalPerson.
- Jaffe_reaction type Thing.
- Jaffe_reaction type Person.
- Jaffe_reaction comment "The Jaffe reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. In 1886, Max Jaffe (1841–1911) wrote about its basic principles in the paper Über den Niederschlag, welchen Pikrinsäre in normalem Harn erzeugt und über eine neue Reaction des Kreatinins in which he described the properties of creatinine and picric acid in an alkaline solution.".
- Jaffe_reaction label "Jaffe reaction".
- Jaffe_reaction sameAs m.0nb33c9.
- Jaffe_reaction sameAs Q6121930.
- Jaffe_reaction sameAs Q6121930.
- Jaffe_reaction wasDerivedFrom Jaffe_reaction?oldid=603030096.
- Jaffe_reaction depiction Max_Jaffe.jpg.
- Jaffe_reaction givenName "Jaffe".
- Jaffe_reaction isPrimaryTopicOf Jaffe_reaction.
- Jaffe_reaction name "Jaffe reaction".
- Jaffe_reaction name "Max Jaffe".
- Jaffe_reaction name "reaction, Jaffe".
- Jaffe_reaction surname "reaction".