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- KF-26777 abstract "KF-26777 is a drug which acts as a potent and selective antagonist for the adenosine A3 receptor, with sub-nanomolar affinity (A3 Ki=0.2nM) and high selectivity over the other three adenosine receptor subtypes. Simple xanthine derivatives such as caffeine and DPCPX have generally low affinity for the A3 subtype and must be extended by expanding the ring system and adding an aromatic group to give high A3 affinity and selectivity.".
- KF-26777 iupacName "(2-(4-bromophenyl)-7,8-dihydro-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one".
- KF-26777 thumbnail KF26777_structure.png?width=300.
- KF-26777 wikiPageID "22520295".
- KF-26777 wikiPageRevisionID "591996541".
- KF-26777 br "1".
- KF-26777 c "16".
- KF-26777 h "18".
- KF-26777 hasPhotoCollection KF-26777.
- KF-26777 molecularWeight "376.25".
- KF-26777 n "5".
- KF-26777 o "1".
- KF-26777 smiles "CCCNC1N=CNC1C=4N2CCN=4".
- KF-26777 synonyms "KF-26777".
- KF-26777 verifiedrevid "424749756".
- KF-26777 width "240".
- KF-26777 subject Category:Imidazopurines.
- KF-26777 subject Category:Lactams.
- KF-26777 subject Category:Organobromides.
- KF-26777 type Drug.
- KF-26777 type DrugProduct.
- KF-26777 type FunctionalSubstance.
- KF-26777 comment "KF-26777 is a drug which acts as a potent and selective antagonist for the adenosine A3 receptor, with sub-nanomolar affinity (A3 Ki=0.2nM) and high selectivity over the other three adenosine receptor subtypes. Simple xanthine derivatives such as caffeine and DPCPX have generally low affinity for the A3 subtype and must be extended by expanding the ring system and adding an aromatic group to give high A3 affinity and selectivity.".
- KF-26777 label "KF-26777".
- KF-26777 sameAs m.05zr0c6.
- KF-26777 sameAs Q6328842.
- KF-26777 sameAs Q6328842.
- KF-26777 wasDerivedFrom KF-26777?oldid=591996541.
- KF-26777 depiction KF26777_structure.png.
- KF-26777 isPrimaryTopicOf KF-26777.