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- Killer_activation_receptor abstract "Killer Activation Receptors (KARs) are receptors expressed on the plasmatic membrane of Natural Killer cells (NK cells). KARs work with inhibitory Killer-cell immunoglobulin-like receptors (KIRs), which inactivate them in order to regulate the NK cells functions on hosted or transformed cells. These two kinds of specific receptors have some morphological features in common, such as being transmembrane proteins. The similarities are specially found in the extracellular domains and, therefore, the differences tend to be in the intracellular domains. KARs and KIRs can only do their function in presence of immunoreceptors that contain tyrosine and have an activator or inhibitor function (they are called ITAMs and ITIMs).At first, it was thought that there were only one KAR and one KIR (two-receptor model). In the last decade, lots of different KARs and KIRs, such as NKp46 or NKG2D, have been discovered (opposing-signals model).".
- Killer_activation_receptor thumbnail KAR_imagen.jpg?width=300.
- Killer_activation_receptor wikiPageExternalLink etexto12.htm.
- Killer_activation_receptor wikiPageID "33735571".
- Killer_activation_receptor wikiPageRevisionID "600615380".
- Killer_activation_receptor hasPhotoCollection Killer_activation_receptor.
- Killer_activation_receptor subject Category:Immunology.
- Killer_activation_receptor subject Category:Lymphocytes.
- Killer_activation_receptor subject Category:Receptors.
- Killer_activation_receptor type BloodCell105449268.
- Killer_activation_receptor type BodyPart105220461.
- Killer_activation_receptor type Cell100006484.
- Killer_activation_receptor type FreePhagocyte105451265.
- Killer_activation_receptor type Leukocyte105449959.
- Killer_activation_receptor type LivingThing100004258.
- Killer_activation_receptor type Lymphocyte105451384.
- Killer_activation_receptor type Lymphocytes.
- Killer_activation_receptor type Object100002684.
- Killer_activation_receptor type Part109385911.
- Killer_activation_receptor type Phagocyte105450888.
- Killer_activation_receptor type PhysicalEntity100001930.
- Killer_activation_receptor type Receptor105608868.
- Killer_activation_receptor type Receptors.
- Killer_activation_receptor type SomaticCell105430628.
- Killer_activation_receptor type Structure105225602.
- Killer_activation_receptor type Thing100002452.
- Killer_activation_receptor type Whole100003553.
- Killer_activation_receptor comment "Killer Activation Receptors (KARs) are receptors expressed on the plasmatic membrane of Natural Killer cells (NK cells). KARs work with inhibitory Killer-cell immunoglobulin-like receptors (KIRs), which inactivate them in order to regulate the NK cells functions on hosted or transformed cells. These two kinds of specific receptors have some morphological features in common, such as being transmembrane proteins.".
- Killer_activation_receptor label "Killer activation receptor".
- Killer_activation_receptor sameAs m.0hhs84z.
- Killer_activation_receptor sameAs Q6407544.
- Killer_activation_receptor sameAs Q6407544.
- Killer_activation_receptor sameAs Killer_activation_receptor.
- Killer_activation_receptor wasDerivedFrom Killer_activation_receptor?oldid=600615380.
- Killer_activation_receptor depiction KAR_imagen.jpg.
- Killer_activation_receptor isPrimaryTopicOf Killer_activation_receptor.