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- Kleine–Levin_syndrome abstract "Kleine-Levin syndrome (KLS) is a rare sleep disorder characterized by persistent episodic hypersomnia and cognitive or mood changes. Many patients also experience hyperphagia, hypersexuality and other symptoms. Patients generally experience recurrent episodes of the condition for more than a decade. Individual episodes generally last more than a week but less than a month. The condition greatly affects the personal, professional, and social lives of sufferers, but symptoms spontaneously resolve and seldom cause permanent issues. The severity of symptoms and the course of the disease vary between sufferers. Patients commonly have about 20 episodes over about a decade. Several months generally elapse between episodes. The onset of the condition usually follows a viral infection; several different viruses have been observed to trigger KLS. It is generally only diagnosed after similar conditions have been excluded; MRI, CT scans, lumbar puncture, and toxicology tests are used to rule out other possibilities. The disease's mechanism is not known, but the thalamus is thought to possibly play a role. Tomography has shown hypoperfusion the brains of patients during episodes. KLS is very rare, occurring at a rate of one in a million, which limits research into genetic factors. The condition primarily affects adolescent males, although some patients are female and the age of onset varies. It is most commonly found in Jews in the United States and Israel. There is no known cure, and there is little evidence supporting drug treatment. Lithium has been reported to have limited effects in case reports, decreasing the length of episodes and duration between them in some patients. Stimulants have been shown to promote wakefulness during episodes, but they do not counteract cognitive symptoms or decrease the duration of episodes. The condition is named after Will Kleine and Max Levin, who described cases of the disease in the early 20th century. It was added to the International Classification of Sleep Disorders in 1990.".
- Kleine–Levin_syndrome wikiPageID "3763136".
- Kleine–Levin_syndrome wikiPageRevisionID "604321746".
- Kleine–Levin_syndrome diseasesdb "29520".
- Kleine–Levin_syndrome icd "327.13".
- Kleine–Levin_syndrome icd "G47.8".
- Kleine–Levin_syndrome meshid "D017593".
- Kleine–Levin_syndrome name "Kleine–Levin syndrome".
- Kleine–Levin_syndrome omim "148840".
- Kleine–Levin_syndrome subject Category:Sleep_disorders.
- Kleine–Levin_syndrome type Disease.
- Kleine–Levin_syndrome type Situation.
- Kleine–Levin_syndrome comment "Kleine-Levin syndrome (KLS) is a rare sleep disorder characterized by persistent episodic hypersomnia and cognitive or mood changes. Many patients also experience hyperphagia, hypersexuality and other symptoms. Patients generally experience recurrent episodes of the condition for more than a decade. Individual episodes generally last more than a week but less than a month.".
- Kleine–Levin_syndrome label "Kleine-Levin-Syndrom".
- Kleine–Levin_syndrome label "Kleine–Levin syndrome".
- Kleine–Levin_syndrome label "Sindrome di Kleine-Levin".
- Kleine–Levin_syndrome label "Syndrome de Kleine-Levin".
- Kleine–Levin_syndrome label "Syndroom van Kleine-Levin".
- Kleine–Levin_syndrome label "Síndrome de Kleine-Levin".
- Kleine–Levin_syndrome label "Síndrome de Kleine-Levin".
- Kleine–Levin_syndrome label "Zespół Kleinego-Levina".
- Kleine–Levin_syndrome label "Синдром Клейне — Левина".
- Kleine–Levin_syndrome label "متلازمة كلاين ليفين".
- Kleine–Levin_syndrome label "クライン・レビン症候群".
- Kleine–Levin_syndrome label "克萊恩-萊文症候群".
- Kleine–Levin_syndrome sameAs Kleine%E2%80%93Levin_syndrome.
- Kleine–Levin_syndrome sameAs Kleine-Levin-Syndrom.
- Kleine–Levin_syndrome sameAs Síndrome_de_Kleine-Levin.
- Kleine–Levin_syndrome sameAs Syndrome_de_Kleine-Levin.
- Kleine–Levin_syndrome sameAs Sindrom_Kleine-Levin.
- Kleine–Levin_syndrome sameAs Sindrome_di_Kleine-Levin.
- Kleine–Levin_syndrome sameAs クライン・レビン症候群.
- Kleine–Levin_syndrome sameAs Syndroom_van_Kleine-Levin.
- Kleine–Levin_syndrome sameAs Zespół_Kleinego-Levina.
- Kleine–Levin_syndrome sameAs Síndrome_de_Kleine-Levin.
- Kleine–Levin_syndrome sameAs Q613809.
- Kleine–Levin_syndrome sameAs Q613809.
- Kleine–Levin_syndrome wasDerivedFrom Kleine–Levin_syndrome?oldid=604321746.