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- LR132 abstract "LR132 or (+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.1 nM for the sigma-1 receptor and more than 350 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with LR132 significantly decreases the convulsivity and lethality of cocaine.".
- LR132 casNumber "135211-15-3".
- LR132 iupacName "(+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine".
- LR132 thumbnail LR132.png?width=300.
- LR132 wikiPageID "36174213".
- LR132 wikiPageRevisionID "540046000".
- LR132 c "18".
- LR132 casNumber "135211".
- LR132 cl "2".
- LR132 h "26".
- LR132 hasPhotoCollection LR132.
- LR132 iupacName "-34".
- LR132 molecularWeight "341.32".
- LR132 n "2".
- LR132 subject Category:Sigma_antagonists.
- LR132 type Drug.
- LR132 type FunctionalSubstance.
- LR132 comment "LR132 or (+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.1 nM for the sigma-1 receptor and more than 350 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with LR132 significantly decreases the convulsivity and lethality of cocaine.".
- LR132 label "LR132".
- LR132 sameAs m.0k0n_23.
- LR132 sameAs Q6459781.
- LR132 sameAs Q6459781.
- LR132 wasDerivedFrom LR132?oldid=540046000.
- LR132 depiction LR132.png.
- LR132 isPrimaryTopicOf LR132.