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- Limb_bud abstract "The limb bud is a structure formed early in limb development. As a result of interactions between the ectoderm and underlying mesoderm, formation occurs roughly around the fourth week of development as mesenchymal cells from the lateral plate mesoderm and the somites begin to proliferate to the point where they create a bulge under the ectodermal cells above. The limb bud remains active throughout much of limb development, and its signaling stimulates formation of another signaling center, the apical ectodermal ridge (AER) as well as formation of the zone of polarizing activity (ZPA) within the mesenchyme. The mesenchymal cells of the limb bud, which stimulate AER formation as well as maintain AER activity, determine what type of limb will form. ZPA signaling will establish polarity of the limb, as well as sustain proper AER activity.".
- Limb_bud precursor Lateral_plate_mesoderm.
- Limb_bud wikiPageID "8149905".
- Limb_bud wikiPageRevisionID "600004984".
- Limb_bud code "TE E5.0.3.0.0.0.5".
- Limb_bud hasPhotoCollection Limb_bud.
- Limb_bud name "Limb Bud".
- Limb_bud precursor Lateral_plate_mesoderm.
- Limb_bud subject Category:Embryology.
- Limb_bud type Abstraction100002137.
- Limb_bud type Biology106037666.
- Limb_bud type Cognition100023271.
- Limb_bud type Content105809192.
- Limb_bud type Discipline105996646.
- Limb_bud type Embryology106071426.
- Limb_bud type KnowledgeDomain105999266.
- Limb_bud type LifeScience106037298.
- Limb_bud type NaturalScience106000400.
- Limb_bud type PsychologicalFeature100023100.
- Limb_bud type Science105999797.
- Limb_bud type AnatomicalStructure.
- Limb_bud type Embryology.
- Limb_bud type AnimalBodyPart.
- Limb_bud type Embryology.
- Limb_bud type BiologicalObject.
- Limb_bud comment "The limb bud is a structure formed early in limb development. As a result of interactions between the ectoderm and underlying mesoderm, formation occurs roughly around the fourth week of development as mesenchymal cells from the lateral plate mesoderm and the somites begin to proliferate to the point where they create a bulge under the ectodermal cells above.".
- Limb_bud label "Limb bud".
- Limb_bud sameAs m.026tf0h.
- Limb_bud sameAs Q6548937.
- Limb_bud sameAs Q6548937.
- Limb_bud sameAs Limb_bud.
- Limb_bud wasDerivedFrom Limb_bud?oldid=600004984.
- Limb_bud isPrimaryTopicOf Limb_bud.
- Limb_bud name "Limb Bud".