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- Lomitapide abstract "Lomitapide (INN, marketed as Juxtapid in the US and as Lojuxta in the EU) is a drug for the treatment of familial hypercholesterolemia, developed by Aegerion Pharmaceuticals.It has been tested in clinical trials as single treatment and in combinations with atorvastatin, ezetimibe and fenofibrate.The US Food and Drug Administration (FDA) approved lomitapide on 21 December 2012, as an orphan drug to reduce LDL cholesterol, total cholesterol, apolipoprotein B, and non-high-density lipoprotein (non-HDL) cholesterol in patients with homozygous familial hypercholesterolemia (HoFH).On 31 May 2013 the European Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion with a unanimous vote recommending a marketing authorization for lomitapide. On 31 July 2013 the European Commission approved lomitapide as an adjunct to a low-fat diet and other lipid-lowering medicinal products with or without low density lipoprotein (LDL) apheresis in adult patients with HoFH.".
- Lomitapide atcPrefix "C10".
- Lomitapide atcSuffix "AX12".
- Lomitapide casNumber "182431-12-5".
- Lomitapide casSupplemental "(mesilate)".
- Lomitapide chEBI "72297".
- Lomitapide fdaUniiCode "82KUB0583F".
- Lomitapide iupacName "N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]2-yl]carbonyl]amino]-1-piperidinyl]butyl]9H-fluoren-9-carboxamde".
- Lomitapide pubchem "9853053".
- Lomitapide thumbnail Lomitapide_skeletal.svg?width=300.
- Lomitapide wikiPageExternalLink 203858s000lbl.pdf.
- Lomitapide wikiPageID "21559841".
- Lomitapide wikiPageRevisionID "586906500".
- Lomitapide atcPrefix "10.0".
- Lomitapide atcSuffix "AX12".
- Lomitapide c "39".
- Lomitapide casNumber "182431".
- Lomitapide chebi "72297".
- Lomitapide f "6".
- Lomitapide h "37".
- Lomitapide hasPhotoCollection Lomitapide.
- Lomitapide iupacName "N--9-[4-[4-[[[4'-[1,1'-biphenyl]2-yl]carbonyl]amino]-1-piperidinyl]butyl]9H-fluoren-9-carboxamde".
- Lomitapide kegg "D09637".
- Lomitapide legalUs "Rx-only".
- Lomitapide licenceEu "Lojuxta".
- Lomitapide licenceUs "Lomitapide".
- Lomitapide molecularWeight "693.719".
- Lomitapide n "3".
- Lomitapide o "2".
- Lomitapide pregnancyUs "X".
- Lomitapide pubchem "9853053".
- Lomitapide routesOfAdministration "Oral".
- Lomitapide smiles "FCc5ccc-c1ccccc1CNC4CCNCCCCC2c3ccccc3-c6ccccc26".
- Lomitapide stdinchi "1".
- Lomitapide stdinchikey "MBBCVAKAJPKAKM-UHFFFAOYSA-N".
- Lomitapide synonyms "AEGR-773, BMS-201038".
- Lomitapide tradename "Juxtapid , Lojuxta".
- Lomitapide unii "82".
- Lomitapide verifiedfields "changed".
- Lomitapide verifiedrevid "444364270".
- Lomitapide watchedfields "changed".
- Lomitapide subject Category:Amides.
- Lomitapide subject Category:Benzamides.
- Lomitapide subject Category:Biphenyls.
- Lomitapide subject Category:Fluorenes.
- Lomitapide subject Category:Hypolipidemic_agents.
- Lomitapide subject Category:Organofluorides.
- Lomitapide subject Category:Piperidines.
- Lomitapide type Abstraction100002137.
- Lomitapide type Amide114724264.
- Lomitapide type Amides.
- Lomitapide type Chemical114806838.
- Lomitapide type Compound114818238.
- Lomitapide type Material114580897.
- Lomitapide type Matter100020827.
- Lomitapide type OrganicCompound114727670.
- Lomitapide type Part113809207.
- Lomitapide type PhysicalEntity100001930.
- Lomitapide type Relation100031921.
- Lomitapide type Substance100019613.
- Lomitapide type Drug.
- Lomitapide type FunctionalSubstance.
- Lomitapide comment "Lomitapide (INN, marketed as Juxtapid in the US and as Lojuxta in the EU) is a drug for the treatment of familial hypercholesterolemia, developed by Aegerion Pharmaceuticals.It has been tested in clinical trials as single treatment and in combinations with atorvastatin, ezetimibe and fenofibrate.The US Food and Drug Administration (FDA) approved lomitapide on 21 December 2012, as an orphan drug to reduce LDL cholesterol, total cholesterol, apolipoprotein B, and non-high-density lipoprotein (non-HDL) cholesterol in patients with homozygous familial hypercholesterolemia (HoFH).On 31 May 2013 the European Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion with a unanimous vote recommending a marketing authorization for lomitapide. ".
- Lomitapide label "Lomitapid".
- Lomitapide label "Lomitapida".
- Lomitapide label "Lomitapide".
- Lomitapide label "Lomitapide".
- Lomitapide sameAs Lomitapid.
- Lomitapide sameAs Lomitapide.
- Lomitapide sameAs Lomitapida.
- Lomitapide sameAs m.05h4tv6.
- Lomitapide sameAs Q1268941.
- Lomitapide sameAs Q1268941.
- Lomitapide sameAs Lomitapide.
- Lomitapide wasDerivedFrom Lomitapide?oldid=586906500.
- Lomitapide depiction Lomitapide_skeletal.svg.
- Lomitapide isPrimaryTopicOf Lomitapide.