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- Lonafarnib abstract "Lonafarnib is a farnesyltransferase inhibitor (FTI) that is being investigated in a human clinical trial as a potential treatment for progeria.Lonafarnib is a synthetic tricyclic derivative of carboxamide with antineoplastic properties. As such, it is used primarily for cancer treatment. For those with progeria, research has shown that the drug reduces the prevalence of stroke and transient ischemic attack, and the prevalence and frequency of headaches while taking the medication. A phase II clinical trial was completed in 2012, which showed that a cocktail of drugs that included lonafarnib and two other drugs, met clinical efficacy endpoints that improved the height and diminished the rigidity of the bones of progeria patients.".
- Lonafarnib fdaUniiCode "IOW153004F".
- Lonafarnib iupacName "(4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide)".
- Lonafarnib thumbnail Lonafarnib.png?width=300.
- Lonafarnib wikiPageExternalLink experimental-drug-is-first-to-help-kids-with-premature-aging-disease?.
- Lonafarnib wikiPageID "13494983".
- Lonafarnib wikiPageRevisionID "600904236".
- Lonafarnib hasPhotoCollection Lonafarnib.
- Lonafarnib imagefile "Lonafarnib.png".
- Lonafarnib imagesize "200".
- Lonafarnib iupacname "(4--1-piperidinecarboxamide)".
- Lonafarnib othernames "Sarasar , SCH 66336".
- Lonafarnib unii "IOW153004F".
- Lonafarnib verifiedfields "changed".
- Lonafarnib verifiedrevid "462093478".
- Lonafarnib subject Category:Benzocycloheptapyridines.
- Lonafarnib subject Category:Farnesyltransferase_inhibitors.
- Lonafarnib subject Category:Organobromides.
- Lonafarnib subject Category:Organochlorides.
- Lonafarnib subject Category:Piperidines.
- Lonafarnib subject Category:Ureas.
- Lonafarnib type Abstraction100002137.
- Lonafarnib type Chemical114806838.
- Lonafarnib type Compound114818238.
- Lonafarnib type Material114580897.
- Lonafarnib type Matter100020827.
- Lonafarnib type OrganicCompound114727670.
- Lonafarnib type Part113809207.
- Lonafarnib type PhysicalEntity100001930.
- Lonafarnib type Relation100031921.
- Lonafarnib type Substance100019613.
- Lonafarnib type Urea115085472.
- Lonafarnib type Ureas.
- Lonafarnib type ChemicalCompound.
- Lonafarnib type ChemicalSubstance.
- Lonafarnib type ChemicalSubstanceType.
- Lonafarnib type ChemicalObject.
- Lonafarnib type Thing.
- Lonafarnib comment "Lonafarnib is a farnesyltransferase inhibitor (FTI) that is being investigated in a human clinical trial as a potential treatment for progeria.Lonafarnib is a synthetic tricyclic derivative of carboxamide with antineoplastic properties. As such, it is used primarily for cancer treatment. For those with progeria, research has shown that the drug reduces the prevalence of stroke and transient ischemic attack, and the prevalence and frequency of headaches while taking the medication.".
- Lonafarnib label "Lonafarnib".
- Lonafarnib label "Lonafarnib".
- Lonafarnib sameAs Lonafarnib.
- Lonafarnib sameAs m.03c764f.
- Lonafarnib sameAs Q3258910.
- Lonafarnib sameAs Q3258910.
- Lonafarnib sameAs Lonafarnib.
- Lonafarnib wasDerivedFrom Lonafarnib?oldid=600904236.
- Lonafarnib depiction Lonafarnib.png.
- Lonafarnib isPrimaryTopicOf Lonafarnib.