Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Lorazepam> ?p ?o. }
- Lorazepam abstract "Lorazepam (trademarked as Ativan or Orfidal) is a high-potency, intermediate-duration, 3-hydroxy benzodiazepine drug, often used to treat anxiety disorders. Lorazepam has all six intrinsic benzodiazepine effects: anxiolysis, anterograde amnesia, sedation/hypnosis, anticonvulsion, antiemesis and muscle relaxation. Lorazepam is used for the short-term treatment of anxiety, insomnia, acute seizures including status epilepticus, and sedation of hospitalized patients, as well as sedation of aggressive patients. Lorazepam is also the most common benzodiazepine used to decrease the likelihood of agitation and seizures in patients who have overdosed on stimulant drugs.Lorazepam's effects are of intermediate duration. Similar to other benzodiazepines, it exerts its therapeutic effects via its interaction at benzodiazepine binding sites, which are located on GABAA receptors in the central nervous system. Although its half-life is shorter than that of other benzodiazepines, its affinity for its receptor translates to a longer duration of action relative to other benzodiazepines, but still shorter than those of diazepam and chlordiazepoxide following a single IV administration.After its introduction in 1977, Lorazepam's principal use was in treating anxiety. Among benzodiazepines, Lorazepam has a relatively high physical addiction potential. Lorazepam also has misuse potential; the main types of misuse are for recreational purposes or continued use against medical advice. Its sedative-hypnotic and anterograde amnesic properties are sometimes used for criminal purposes in a manner similar to GHB.Long-term effects of benzodiazepines include tolerance, dependence, a benzodiazepine withdrawal syndrome, and cognitive impairments which may not completely reverse after cessation of treatment; however, for most patients, cognitive impairment is not severe. Withdrawal symptoms can range from anxiety and insomnia to seizures and psychosis. Due to tolerance and dependence, lorazepam is recommended for short-term use, up to two to four weeks only. Adverse effects, including anterograde amnesia, depression and paradoxical effects such as excitement or worsening of seizures, may occur. Children and the elderly are more sensitive to the adverse effects of benzodiazepines. Lorazepam impairs body balance and standing steadiness and is associated with falls and hip fractures in the elderly.".
- Lorazepam atcPrefix "N05".
- Lorazepam atcSuffix "BA06".
- Lorazepam bioavailability "85.0".
- Lorazepam casNumber "846-49-1".
- Lorazepam drugbank "DB00186".
- Lorazepam fdaUniiCode "O26FZP769L".
- Lorazepam iupacName "(RS)-7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one".
- Lorazepam pubchem "3958".
- Lorazepam thumbnail Lorazepam.svg?width=300.
- Lorazepam wikiPageExternalLink index.htm.
- Lorazepam wikiPageExternalLink dpdirect.jsp?name=Lorazepam.
- Lorazepam wikiPageExternalLink ativan.pdf.
- Lorazepam wikiPageExternalLink lorazepam.htm.
- Lorazepam wikiPageExternalLink lorazepam.html.
- Lorazepam wikiPageExternalLink pim223.htm.
- Lorazepam wikiPageExternalLink Lorzemtab.htm.
- Lorazepam wikiPageExternalLink ntlc_benzodiazepines.pdf.
- Lorazepam wikiPageExternalLink loraz.htm.
- Lorazepam wikiPageID "244115".
- Lorazepam wikiPageRevisionID "606045464".
- Lorazepam atcPrefix "N05".
- Lorazepam atcSuffix "BA06".
- Lorazepam bioavailability "85".
- Lorazepam c "15".
- Lorazepam casNumber "846".
- Lorazepam chembl "580".
- Lorazepam chemspiderid "3821".
- Lorazepam cl "2".
- Lorazepam dependencyLiability "Moderate".
- Lorazepam drugbank "DB00186".
- Lorazepam eliminationHalfLife "57600.0".
- Lorazepam excretion Kidney.
- Lorazepam h "10".
- Lorazepam hasPhotoCollection Lorazepam.
- Lorazepam image "Lorazepam3Dan.gif".
- Lorazepam inchi "1".
- Lorazepam iupacName "-7".
- Lorazepam kegg "D00365".
- Lorazepam legalCa "Schedule IV".
- Lorazepam legalUk "CD POM".
- Lorazepam legalUs "Schedule IV".
- Lorazepam medlineplus "a682053".
- Lorazepam metabolism Glucuronidation.
- Lorazepam metabolism Liver.
- Lorazepam molecularWeight "321.2".
- Lorazepam n "2".
- Lorazepam o "2".
- Lorazepam pregnancyUs "D".
- Lorazepam pubchem "3958".
- Lorazepam routesOfAdministration "Oral, intramuscular, intravenous, sublingual, and transdermal".
- Lorazepam smiles "ClC1=CC=CC=C1C2=NCO".
- Lorazepam stdinchi "1".
- Lorazepam stdinchikey "DIWRORZWFLOCLC-UHFFFAOYSA-N".
- Lorazepam synonyms "O-Chloroxazepam, L-Lorazepam Acetate".
- Lorazepam tradename "Ativan and others".
- Lorazepam unii "O26FZP769L".
- Lorazepam verifiedfields "changed".
- Lorazepam verifiedrevid "419619495".
- Lorazepam watchedfields "changed".
- Lorazepam width "200".
- Lorazepam width "250".
- Lorazepam subject Category:Antiemetics.
- Lorazepam subject Category:Benzodiazepines.
- Lorazepam subject Category:Drugs_acting_on_the_nervous_system.
- Lorazepam subject Category:GABA_agonists.
- Lorazepam subject Category:Lactams.
- Lorazepam subject Category:Organochlorides.
- Lorazepam type Drug.
- Lorazepam type DrugProduct.
- Lorazepam type FunctionalSubstance.
- Lorazepam comment "Lorazepam (trademarked as Ativan or Orfidal) is a high-potency, intermediate-duration, 3-hydroxy benzodiazepine drug, often used to treat anxiety disorders. Lorazepam has all six intrinsic benzodiazepine effects: anxiolysis, anterograde amnesia, sedation/hypnosis, anticonvulsion, antiemesis and muscle relaxation.".
- Lorazepam label "Lorazepam".
- Lorazepam label "Lorazepam".
- Lorazepam label "Lorazepam".
- Lorazepam label "Lorazepam".
- Lorazepam label "Lorazepam".
- Lorazepam label "Lorazepam".
- Lorazepam label "Lorazepam".
- Lorazepam label "Lorazépam".
- Lorazepam label "Лоразепам".
- Lorazepam label "ロラゼパム".
- Lorazepam label "劳拉西泮".
- Lorazepam sameAs Lorazepam.
- Lorazepam sameAs Lorazepam.
- Lorazepam sameAs Lorazepam.
- Lorazepam sameAs Lorazépam.
- Lorazepam sameAs Lorazepam.
- Lorazepam sameAs ロラゼパム.
- Lorazepam sameAs 로라제팜.
- Lorazepam sameAs Lorazepam.
- Lorazepam sameAs Lorazepam.
- Lorazepam sameAs Lorazepam.
- Lorazepam sameAs m.01kcsd.
- Lorazepam sameAs Q408265.
- Lorazepam sameAs Q408265.
- Lorazepam sameAs lorazepam.
- Lorazepam sameAs DB00186.
- Lorazepam sameAs 3958.
- Lorazepam wasDerivedFrom Lorazepam?oldid=606045464.