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- Malignant_hyperthermia abstract "Malignant hyperthermia (MH) or malignant hyperpyrexia is a rare life-threatening condition that is usually triggered by exposure to certain drugs used for general anesthesia, specifically the volatile anesthetic agents and the neuromuscular blocking agent, succinylcholine. In susceptible individuals, these drugs can induce a drastic and uncontrolled increase in skeletal muscle oxidative metabolism, which overwhelms the body's capacity to supply oxygen, remove carbon dioxide, and regulate body temperature, eventually leading to circulatory collapse and death if not treated quickly.Susceptibility to MH is often inherited as an autosomal dominant disorder, for which there are at least 6 genetic loci of interest, most prominently the ryanodine receptor gene (RYR1). MH susceptibility is phenotypically and genetically related to central core disease (CCD), an autosomal dominant disorder characterized both by MH symptoms and myopathy. MH is usually revealed by anesthesia, or when a family member develops the symptoms. There is no simple, straightforward test to diagnose the condition. When MH develops during a procedure, treatment with dantrolene sodium is usually initiated; dantrolene and the avoidance of inhaled anesthesia in susceptible people have markedly reduced the mortality from this condition.".
- Malignant_hyperthermia diseasesdb "7776".
- Malignant_hyperthermia icd10 "T88.3".
- Malignant_hyperthermia icd9 "995.86".
- Malignant_hyperthermia medlineplus "001315".
- Malignant_hyperthermia meshId "D008305".
- Malignant_hyperthermia omim "145600".
- Malignant_hyperthermia thumbnail PBB_Protein_RYR1_image.jpg?width=300.
- Malignant_hyperthermia wikiPageExternalLink mh.
- Malignant_hyperthermia wikiPageExternalLink www.mhaus.org.
- Malignant_hyperthermia wikiPageExternalLink NBK1146.
- Malignant_hyperthermia wikiPageID "722421".
- Malignant_hyperthermia wikiPageRevisionID "599992693".
- Malignant_hyperthermia caption "Abnormalities in the Ryanodine receptor 1 gene are commonly detected in people with have experienced an episode of malignant hyperthermia, and may be used to determine the risk of episodes in their relatives".
- Malignant_hyperthermia diseasesdb "7776".
- Malignant_hyperthermia genereviewsname "Malignant Hyperthermia Susceptibility".
- Malignant_hyperthermia genereviewsnbk "NBK1146".
- Malignant_hyperthermia hasPhotoCollection Malignant_hyperthermia.
- Malignant_hyperthermia icd "995.86".
- Malignant_hyperthermia icd "T88.3".
- Malignant_hyperthermia medlineplus "1315".
- Malignant_hyperthermia meshid "D008305".
- Malignant_hyperthermia name "Malignant hyperthermia".
- Malignant_hyperthermia omim "145600".
- Malignant_hyperthermia wordnet_type synset-disease-noun-1.
- Malignant_hyperthermia subject Category:Anesthesia.
- Malignant_hyperthermia subject Category:Channelopathy.
- Malignant_hyperthermia subject Category:Complications_of_surgical_and_medical_care.
- Malignant_hyperthermia subject Category:Rare_diseases.
- Malignant_hyperthermia type Disease.
- Malignant_hyperthermia type AilmentCondition.
- Malignant_hyperthermia type Situation.
- Malignant_hyperthermia comment "Malignant hyperthermia (MH) or malignant hyperpyrexia is a rare life-threatening condition that is usually triggered by exposure to certain drugs used for general anesthesia, specifically the volatile anesthetic agents and the neuromuscular blocking agent, succinylcholine.".
- Malignant_hyperthermia label "Hipertermia maligna".
- Malignant_hyperthermia label "Hipertermia maligna".
- Malignant_hyperthermia label "Hipertermia złośliwa".
- Malignant_hyperthermia label "Hyperthermie maligne".
- Malignant_hyperthermia label "Ipertermia maligna".
- Malignant_hyperthermia label "Malignant hyperthermia".
- Malignant_hyperthermia label "Maligne Hyperthermie".
- Malignant_hyperthermia label "Maligne hyperthermie".
- Malignant_hyperthermia label "Злокачественная гипертермия".
- Malignant_hyperthermia label "悪性高熱症".
- Malignant_hyperthermia sameAs Maligne_Hyperthermie.
- Malignant_hyperthermia sameAs Hipertermia_maligna.
- Malignant_hyperthermia sameAs Hyperthermie_maligne.
- Malignant_hyperthermia sameAs Ipertermia_maligna.
- Malignant_hyperthermia sameAs 悪性高熱症.
- Malignant_hyperthermia sameAs Maligne_hyperthermie.
- Malignant_hyperthermia sameAs Hipertermia_złośliwa.
- Malignant_hyperthermia sameAs Hipertermia_maligna.
- Malignant_hyperthermia sameAs m.035pwp.
- Malignant_hyperthermia sameAs Q1585081.
- Malignant_hyperthermia sameAs Q1585081.
- Malignant_hyperthermia sameAs C0024591.
- Malignant_hyperthermia wasDerivedFrom Malignant_hyperthermia?oldid=599992693.
- Malignant_hyperthermia depiction PBB_Protein_RYR1_image.jpg.
- Malignant_hyperthermia isPrimaryTopicOf Malignant_hyperthermia.
- Malignant_hyperthermia name "Malignant hyperthermia".