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- Maropitant abstract "Maropitant (trade name Cerenia in the US and other countries), used as maropitant citrate (USAN), is a neurokinin (NK1) receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.Maropitant also has anti-nociceptive (analgesic) properties. In a 2012 study, parenteral maropitant decreased the MAC of sevoflurane in a pain-response model.[citation needed] Epidural administration had no effect. It has also been shown to decrease the MAC of sevoflurane in a cat spay and dog spay model. Whether it has analgesic properties in awake animals remains to be proven, but anecdotal evidence indicates that it is being used for analgesia by many veterinarians. Its mode of action is through inhibition of substance P binding at the NK1 receptor.".
- Maropitant atcPrefix "A04".
- Maropitant atcSuffix "AD90".
- Maropitant fdaUniiCode "4XE2T9H4DH".
- Maropitant iupacName "(7R,8S)-N-[(5-tert-Butyl-2-methoxyphenyl)methyl]-7-[di(phenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine".
- Maropitant pubchem "23724948".
- Maropitant thumbnail Maropitant.png?width=300.
- Maropitant wikiPageID "16845281".
- Maropitant wikiPageRevisionID "595893313".
- Maropitant atcPrefix "A04".
- Maropitant atcSuffix "AD90".
- Maropitant atcvet "yes".
- Maropitant c "32".
- Maropitant chemspiderid "176804".
- Maropitant h "40".
- Maropitant hasPhotoCollection Maropitant.
- Maropitant inchi "1".
- Maropitant inchikey "PGVSXRHFXJOMGW-YBZGWEFGBR".
- Maropitant iupacName "-N-[methyl]-7-[dimethyl]-1-azabicyclo[2.2.2]octan-8-amine".
- Maropitant legalStatus "veterinary prescription only".
- Maropitant molecularWeight "468.67".
- Maropitant n "2".
- Maropitant o "1".
- Maropitant pubchem "23724948".
- Maropitant routesOfAdministration "Oral, subcutaneous".
- Maropitant smiles "O=CCCCO.O.OC".
- Maropitant stdinchi "1".
- Maropitant stdinchikey "PGVSXRHFXJOMGW-YBZGWEFGSA-N".
- Maropitant unii "4".
- Maropitant verifiedrevid "443993471".
- Maropitant subject Category:Cat_medications.
- Maropitant subject Category:Dog_medications.
- Maropitant subject Category:NK1_receptor_antagonists.
- Maropitant subject Category:Phenol_ethers.
- Maropitant subject Category:Quinuclidines.
- Maropitant type Adversary109773245.
- Maropitant type CausalAgent100007347.
- Maropitant type LivingThing100004258.
- Maropitant type NK1ReceptorAntagonists.
- Maropitant type Object100002684.
- Maropitant type Organism100004475.
- Maropitant type Person100007846.
- Maropitant type PhysicalEntity100001930.
- Maropitant type Whole100003553.
- Maropitant type YagoLegalActor.
- Maropitant type YagoLegalActorGeo.
- Maropitant type Drug.
- Maropitant type DrugProduct.
- Maropitant type FunctionalSubstance.
- Maropitant comment "Maropitant (trade name Cerenia in the US and other countries), used as maropitant citrate (USAN), is a neurokinin (NK1) receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.Maropitant also has anti-nociceptive (analgesic) properties.".
- Maropitant label "Maropitant".
- Maropitant label "Maropitant".
- Maropitant sameAs Maropitant.
- Maropitant sameAs Maropitant.
- Maropitant sameAs m.04082mq.
- Maropitant sameAs Q3849795.
- Maropitant sameAs Q3849795.
- Maropitant sameAs Maropitant.
- Maropitant wasDerivedFrom Maropitant?oldid=595893313.
- Maropitant depiction Maropitant.png.
- Maropitant isPrimaryTopicOf Maropitant.