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- Methanobactin abstract "Methanobactin (mb) is a class of copper-binding and reducing chromophoric peptides initially identified in the methanotroph Methylococcus capsulatus Bath - and later in Methylosinus tricasporium OB3b - during the isolation of the membrane-associated or particulate methane monooxygenase (pMMO). It is thought to be secreted to the extracellular media to recruit copper, a critical component of methane monooxygenase, the first enzyme in the series that catalyzes the oxidation of methane into methanol. Methanobactin functions as a chalkophore, similar to iron siderophores, by binding to Cu(II) or Cu(I) then shuttling the copper into the cell. Methanobactin has an extremely high affinity for binding and Cu(I) with a Kd approximating ~1020 M−1 at pH 8.Additionally, methanobactin can reduce Cu(II), which is toxic to cells, to Cu(I), the form used in pMMO. Moreover, different species of methanobactin are hypothesized to be ubiquitous within the biosphere, especially in light of the discovery of molecules produced by other type II methanotrophs that similarly bind and reduce copper (II) to copper (I).".
- Methanobactin thumbnail Methanobactin0b3b.png?width=300.
- Methanobactin wikiPageID "32791702".
- Methanobactin wikiPageRevisionID "507224538".
- Methanobactin hasPhotoCollection Methanobactin.
- Methanobactin subject Category:Cell_biology.
- Methanobactin subject Category:Peptides.
- Methanobactin type Abstraction100002137.
- Methanobactin type Amide114724264.
- Methanobactin type Chemical114806838.
- Methanobactin type Compound114818238.
- Methanobactin type Material114580897.
- Methanobactin type Matter100020827.
- Methanobactin type OrganicCompound114727670.
- Methanobactin type Part113809207.
- Methanobactin type Peptide114743046.
- Methanobactin type Peptides.
- Methanobactin type PhysicalEntity100001930.
- Methanobactin type Relation100031921.
- Methanobactin type Substance100019613.
- Methanobactin comment "Methanobactin (mb) is a class of copper-binding and reducing chromophoric peptides initially identified in the methanotroph Methylococcus capsulatus Bath - and later in Methylosinus tricasporium OB3b - during the isolation of the membrane-associated or particulate methane monooxygenase (pMMO).".
- Methanobactin label "Methanobactin".
- Methanobactin sameAs m.0h3tdh9.
- Methanobactin sameAs Q6823577.
- Methanobactin sameAs Q6823577.
- Methanobactin sameAs Methanobactin.
- Methanobactin wasDerivedFrom Methanobactin?oldid=507224538.
- Methanobactin depiction Methanobactin0b3b.png.
- Methanobactin isPrimaryTopicOf Methanobactin.