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- Methotrexate_Leucovorin_Rescue abstract "Methotrexate (abbreviated MTX) is a cancer drug which kills cells by blocking the normal DNA and RNA synthesis necessary for life. It poisons cells through its similarity to folic acid (Vitamin B9) by blocking the enzymes that normally use it.Its effects can be quickly reversed by administering leucovorin, an activated form of Vitamin B9 that does an end run around the metabolic pathway that methotrexate blocks. Thus leucovorin is a true antidote for methotrexate.Cancer cells grow aggressively and consume nutrients at a higher rate than most other body tissues except for brain and kidney. Long term administration of methotrexate can cause damage to the white matter of the brain, the myelin sheaths that insulate the nerve cells. Damage to white matter is called leucoencephalopathy.".
- Methotrexate_Leucovorin_Rescue thumbnail MTXLeuco.png?width=300.
- Methotrexate_Leucovorin_Rescue wikiPageID "34752058".
- Methotrexate_Leucovorin_Rescue wikiPageRevisionID "598997541".
- Methotrexate_Leucovorin_Rescue hasPhotoCollection Methotrexate_Leucovorin_Rescue.
- Methotrexate_Leucovorin_Rescue subject Category:Antidotes.
- Methotrexate_Leucovorin_Rescue subject Category:Biochemistry.
- Methotrexate_Leucovorin_Rescue subject Category:Chemotherapy.
- Methotrexate_Leucovorin_Rescue subject Category:Poisoning_by_drugs,_medicaments_and_biological_substances.
- Methotrexate_Leucovorin_Rescue type Abstraction100002137.
- Methotrexate_Leucovorin_Rescue type Act100030358.
- Methotrexate_Leucovorin_Rescue type Activity100407535.
- Methotrexate_Leucovorin_Rescue type CancerTreatments.
- Methotrexate_Leucovorin_Rescue type Care100654885.
- Methotrexate_Leucovorin_Rescue type Event100029378.
- Methotrexate_Leucovorin_Rescue type PsychologicalFeature100023100.
- Methotrexate_Leucovorin_Rescue type Treatment100658082.
- Methotrexate_Leucovorin_Rescue type Work100575741.
- Methotrexate_Leucovorin_Rescue type YagoPermanentlyLocatedEntity.
- Methotrexate_Leucovorin_Rescue comment "Methotrexate (abbreviated MTX) is a cancer drug which kills cells by blocking the normal DNA and RNA synthesis necessary for life. It poisons cells through its similarity to folic acid (Vitamin B9) by blocking the enzymes that normally use it.Its effects can be quickly reversed by administering leucovorin, an activated form of Vitamin B9 that does an end run around the metabolic pathway that methotrexate blocks.".
- Methotrexate_Leucovorin_Rescue label "Methotrexate Leucovorin Rescue".
- Methotrexate_Leucovorin_Rescue sameAs m.0j3d__7.
- Methotrexate_Leucovorin_Rescue sameAs Q6823888.
- Methotrexate_Leucovorin_Rescue sameAs Q6823888.
- Methotrexate_Leucovorin_Rescue sameAs Methotrexate_Leucovorin_Rescue.
- Methotrexate_Leucovorin_Rescue wasDerivedFrom Methotrexate_Leucovorin_Rescue?oldid=598997541.
- Methotrexate_Leucovorin_Rescue depiction MTXLeuco.png.
- Methotrexate_Leucovorin_Rescue isPrimaryTopicOf Methotrexate_Leucovorin_Rescue.