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- Methylenetetrahydrofolate_reductase abstract "Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Genetic variation in this gene may influence susceptibility to occlusive vascular disease, neural tube defects, dementia, colon cancer, and acute leukemia, because mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.".
- Methylenetetrahydrofolate_reductase ecNumber "1.5.1.20".
- Methylenetetrahydrofolate_reductase thumbnail MTHFR_active_site.jpg?width=300.
- Methylenetetrahydrofolate_reductase wikiPageID "1334933".
- Methylenetetrahydrofolate_reductase wikiPageRevisionID "601961905".
- Methylenetetrahydrofolate_reductase caption "Ribbon diagram of the active site of E. coli MTHFR. The flavin cofactor is shown interacting with the bound substrate NADH.".
- Methylenetetrahydrofolate_reductase casNumber "9028".
- Methylenetetrahydrofolate_reductase ecNumber "1.5".
- Methylenetetrahydrofolate_reductase goCode "4489".
- Methylenetetrahydrofolate_reductase hasPhotoCollection Methylenetetrahydrofolate_reductase.
- Methylenetetrahydrofolate_reductase iubmbEcNumber "1".
- Methylenetetrahydrofolate_reductase name "methylene tetrahydrofolate reductase [NADH]".
- Methylenetetrahydrofolate_reductase requireManualInspection "no".
- Methylenetetrahydrofolate_reductase updateCitations "yes".
- Methylenetetrahydrofolate_reductase updatePage "yes".
- Methylenetetrahydrofolate_reductase updateProteinBox "yes".
- Methylenetetrahydrofolate_reductase updateSummary "no".
- Methylenetetrahydrofolate_reductase width "292".
- Methylenetetrahydrofolate_reductase subject Category:EC_1.5.1.
- Methylenetetrahydrofolate_reductase subject Category:Human_proteins.
- Methylenetetrahydrofolate_reductase type Abstraction100002137.
- Methylenetetrahydrofolate_reductase type Chemical114806838.
- Methylenetetrahydrofolate_reductase type Compound114818238.
- Methylenetetrahydrofolate_reductase type HumanProteins.
- Methylenetetrahydrofolate_reductase type Macromolecule114944888.
- Methylenetetrahydrofolate_reductase type Material114580897.
- Methylenetetrahydrofolate_reductase type Matter100020827.
- Methylenetetrahydrofolate_reductase type Molecule114682133.
- Methylenetetrahydrofolate_reductase type OrganicCompound114727670.
- Methylenetetrahydrofolate_reductase type Part113809207.
- Methylenetetrahydrofolate_reductase type PhysicalEntity100001930.
- Methylenetetrahydrofolate_reductase type Protein114728724.
- Methylenetetrahydrofolate_reductase type Relation100031921.
- Methylenetetrahydrofolate_reductase type Substance100019613.
- Methylenetetrahydrofolate_reductase type Thing100002452.
- Methylenetetrahydrofolate_reductase type Unit109465459.
- Methylenetetrahydrofolate_reductase type Biomolecule.
- Methylenetetrahydrofolate_reductase type Enzyme.
- Methylenetetrahydrofolate_reductase type BiologicalObject.
- Methylenetetrahydrofolate_reductase comment "Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine.".
- Methylenetetrahydrofolate_reductase label "5,10-méthylènetétrahydrofolate réductase".
- Methylenetetrahydrofolate_reductase label "MTHFR".
- Methylenetetrahydrofolate_reductase label "Methylenetetrahydrofolate reductase".
- Methylenetetrahydrofolate_reductase label "Methylentetrahydrofolat-Reduktase".
- Methylenetetrahydrofolate_reductase label "Metilenetetraidrofolato reduttasi (NAD(P)H)".
- Methylenetetrahydrofolate_reductase label "Reduktaza metylenotetrahydrofolianu".
- Methylenetetrahydrofolate_reductase label "Метилентетрагидрофолатредуктаза".
- Methylenetetrahydrofolate_reductase label "メチレンテトラヒドロ葉酸還元酵素".
- Methylenetetrahydrofolate_reductase sameAs Methylentetrahydrofolat-Reduktase.
- Methylenetetrahydrofolate_reductase sameAs 5,10-méthylènetétrahydrofolate_réductase.
- Methylenetetrahydrofolate_reductase sameAs Metilenetetraidrofolato_reduttasi_(NAD(P)H).
- Methylenetetrahydrofolate_reductase sameAs メチレンテトラヒドロ葉酸還元酵素.
- Methylenetetrahydrofolate_reductase sameAs Reduktaza_metylenotetrahydrofolianu.
- Methylenetetrahydrofolate_reductase sameAs MTHFR.
- Methylenetetrahydrofolate_reductase sameAs m.04tmdk.
- Methylenetetrahydrofolate_reductase sameAs Q424709.
- Methylenetetrahydrofolate_reductase sameAs Q424709.
- Methylenetetrahydrofolate_reductase sameAs MTHFR.
- Methylenetetrahydrofolate_reductase sameAs 18.
- Methylenetetrahydrofolate_reductase sameAs 3917.
- Methylenetetrahydrofolate_reductase sameAs 3918.
- Methylenetetrahydrofolate_reductase sameAs 3920.
- Methylenetetrahydrofolate_reductase sameAs Methylenetetrahydrofolate_reductase.
- Methylenetetrahydrofolate_reductase wasDerivedFrom Methylenetetrahydrofolate_reductase?oldid=601961905.
- Methylenetetrahydrofolate_reductase depiction MTHFR_active_site.jpg.
- Methylenetetrahydrofolate_reductase isPrimaryTopicOf Methylenetetrahydrofolate_reductase.
- Methylenetetrahydrofolate_reductase name "methylene tetrahydrofolate reductase [NAD(P)H]".