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- Metopon abstract "Metopon (5-methyldihydromorphone) is an opiate analogue that is a methylated derivative of hydromorphone which was invented in 1929 as an analgesic.Metopon is sometimes used in medicine, although longer acting than hydromorphone, Metopon is less potent and its oral bioavailability is fairly low. Generally, Metopon has few advantages to distinguish it from other, more commonly used opioid analgesics, although it does have a slightly lower tendency to produce nausea and respiratory depression compared to morphine.In Canada, as of 1948, the hydrochloride of metopon (free base conversion ratio 0.891, molecular weight 335.8) was available only for oral administration for malignant pain and for maintenance of those habituated to morphine; the only dosage form available was singly scored 8 mg tablets. It was manufactured by Parke, Davis, & Co., and was only for sale to doctors and hospitals. Parke, Davis & Co. did not sell metopon to pharmacies. It is unknown whether metopon tablets are still manufactured and sold in Canada.Metopon tablets, ampoules, and suppositories are available in Switzerland, Austria, Germany, and other countries in Continental Europe and the drug is used in Patient Controlled Analgesia pumps for severe chronic pain in particular. Metopon is listed under Schedule II of the US Controlled Substances Act 1970, meaning it has an accepted medical use, but at this time it is not produced commercially and is seen only in laboratory research. It did see some use in medicine — oncology in particular — in the USA in the 1950s.CAS number 124-92-5 (Metopon hydrochloride)".
- Metopon atcPrefix "none".
- Metopon casNumber "143-52-2".
- Metopon fdaUniiCode "94XZ1CC69D".
- Metopon iupacName "5β-methyl-7,8-dihydromorphin-6-one".
- Metopon pubchem "5359353".
- Metopon thumbnail Metopon_structure.svg?width=300.
- Metopon wikiPageID "9710950".
- Metopon wikiPageRevisionID "603354458".
- Metopon atcPrefix "none".
- Metopon c "18".
- Metopon casNumber "143".
- Metopon chemspiderid "4514264".
- Metopon h "21".
- Metopon hasPhotoCollection Metopon.
- Metopon inchi "1".
- Metopon inchikey "NPZXCTIHHUUEEJ-CMKMFDCUBE".
- Metopon iupacName "5".
- Metopon molecularWeight "299.364".
- Metopon n "1".
- Metopon o "3".
- Metopon pubchem "5359353".
- Metopon smiles "O=C4[C@@]5C".
- Metopon stdinchi "1".
- Metopon stdinchikey "NPZXCTIHHUUEEJ-CMKMFDCUSA-N".
- Metopon unii "94".
- Metopon verifiedrevid "451353688".
- Metopon width "160".
- Metopon subject Category:Ketones.
- Metopon subject Category:Morphinans.
- Metopon subject Category:Mu-opioid_agonists.
- Metopon subject Category:Phenols.
- Metopon subject Category:Semisynthetic_opioids.
- Metopon type Abstraction100002137.
- Metopon type Chemical114806838.
- Metopon type Compound114818238.
- Metopon type Ketone114926294.
- Metopon type Ketones.
- Metopon type Material114580897.
- Metopon type Matter100020827.
- Metopon type OrganicCompound114727670.
- Metopon type Part113809207.
- Metopon type Phenol114989545.
- Metopon type Phenols.
- Metopon type PhysicalEntity100001930.
- Metopon type Relation100031921.
- Metopon type Substance100019613.
- Metopon type Drug.
- Metopon type DrugProduct.
- Metopon type FunctionalSubstance.
- Metopon comment "Metopon (5-methyldihydromorphone) is an opiate analogue that is a methylated derivative of hydromorphone which was invented in 1929 as an analgesic.Metopon is sometimes used in medicine, although longer acting than hydromorphone, Metopon is less potent and its oral bioavailability is fairly low.".
- Metopon label "Metopon".
- Metopon label "Metopon".
- Metopon label "Метопон".
- Metopon sameAs Metopon.
- Metopon sameAs m.02pptns.
- Metopon sameAs Q2667888.
- Metopon sameAs Q2667888.
- Metopon sameAs Metopon.
- Metopon wasDerivedFrom Metopon?oldid=603354458.
- Metopon depiction Metopon_structure.svg.
- Metopon isPrimaryTopicOf Metopon.