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- Minocycline abstract "Minocycline (INN) is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group. It is a bacteriostatic antibiotic, classified as a long-acting type. As a result of its long half-life it generally has serum levels 2–4 times that of the simple water-soluble tetracyclines (150 mg giving 16 times the activity levels compared with 250 mg of tetracycline at 24–48 hours).Minocycline is the most lipid-soluble of the tetracycline-class antibiotics, giving it the greatest penetration into the prostate and brain, but also the greatest amount of central nervous system (CNS)-related side effects, such as vertigo. A common side effect is diarrhea. Uncommon side effects (with prolonged therapy) include skin discolouration and autoimmune disorders that are not seen with other drugs in the class.Minocycline is a relatively poor tetracycline-class antibiotic choice for urinary pathogens sensitive to this antibiotic class, as its solubility in water and levels in the urine are less than all other tetracyclines. Minocycline is metabolized by the liver and has poor urinary excretion.Minocycline is not a naturally-occurring antibiotic, but was synthesized semi-synthetically from natural tetracycline antibiotics by Lederle Laboratories in 1972, and marketed by them under the brand name Minocin.".
- Minocycline atcPrefix "J01".
- Minocycline atcSuffix "AA08".
- Minocycline bioavailability "100.0".
- Minocycline casNumber "10118-90-8".
- Minocycline chEBI "50694".
- Minocycline drugbank "DB01017".
- Minocycline fdaUniiCode "FYY3R43WGO".
- Minocycline iupacName "(2E,4S,4aR,5aS,12aR)- 2-(amino-hydroxy-methylidene)- 4,7-bis(dimethylamino)- 10,11,12a-trihydroxy-4a,5,5a,6- tetrahydro-4H-tetracene- 1,3,12-trione".
- Minocycline pubchem "24960".
- Minocycline thumbnail Minocycline_structure.svg?width=300.
- Minocycline wikiPageExternalLink NCT00409747.
- Minocycline wikiPageExternalLink minocycline.html.
- Minocycline wikiPageExternalLink article.htm.
- Minocycline wikiPageExternalLink Minotabtab.htm.
- Minocycline wikiPageID "249270".
- Minocycline wikiPageRevisionID "606045872".
- Minocycline atcPrefix "J01".
- Minocycline atcSuffix "AA08".
- Minocycline bioavailability "100.0".
- Minocycline c "23".
- Minocycline casNumber "10118".
- Minocycline chebi "50694".
- Minocycline chembl "1434".
- Minocycline chemspiderid "16735907".
- Minocycline dailymedid "24184".
- Minocycline drugbank "DB01017".
- Minocycline eliminationHalfLife "79200.0".
- Minocycline excretion "mostly fecal, rest renal".
- Minocycline h "27".
- Minocycline hasPhotoCollection Minocycline.
- Minocycline image "Minocycline-from-xtal-PDB-2DRD-3D-balls.png".
- Minocycline inchi "1".
- Minocycline iupacName "-2".
- Minocycline kegg "D05045".
- Minocycline legalAu "S4".
- Minocycline legalUs "Rx-only".
- Minocycline licenceUs "Minocycline".
- Minocycline medlineplus "a682101".
- Minocycline metabolism Liver.
- Minocycline molecularWeight "457.477".
- Minocycline n "3".
- Minocycline o "7".
- Minocycline pregnancyUs "D".
- Minocycline pubchem "24960".
- Minocycline routesOfAdministration "oral".
- Minocycline smiles "CN[C@@H]1C=CC[C@@]2C=C3/Cc4ccccNC".
- Minocycline stdinchi "1".
- Minocycline stdinchikey "DYKFCLLONBREIL-KVUCHLLUSA-N".
- Minocycline tradename "Minocin".
- Minocycline unii "FYY3R43WGO".
- Minocycline verifiedfields "changed".
- Minocycline verifiedrevid "413871574".
- Minocycline watchedfields "changed".
- Minocycline subject Category:Anti-acne_preparations.
- Minocycline subject Category:Neuroprotective_agents.
- Minocycline subject Category:Tetracycline_antibiotics.
- Minocycline type Drug.
- Minocycline type DrugProduct.
- Minocycline type FunctionalSubstance.
- Minocycline comment "Minocycline (INN) is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group. It is a bacteriostatic antibiotic, classified as a long-acting type.".
- Minocycline label "Minociclina".
- Minocycline label "Minociclina".
- Minocycline label "Minociclina".
- Minocycline label "Minocyclin".
- Minocycline label "Minocycline".
- Minocycline label "Minocycline".
- Minocycline label "Minocyklina".
- Minocycline label "Миноциклин".
- Minocycline label "ミノサイクリン".
- Minocycline label "米诺环素".
- Minocycline sameAs Minocyclin.
- Minocycline sameAs Minociclina.
- Minocycline sameAs Minocycline.
- Minocycline sameAs Minociclina.
- Minocycline sameAs ミノサイクリン.
- Minocycline sameAs Minocyklina.
- Minocycline sameAs Minociclina.
- Minocycline sameAs m.01k_w2.
- Minocycline sameAs Q415336.
- Minocycline sameAs Q415336.
- Minocycline sameAs minocycline.
- Minocycline sameAs DB01017.
- Minocycline sameAs 4200.
- Minocycline wasDerivedFrom Minocycline?oldid=606045872.
- Minocycline depiction Minocycline_structure.svg.
- Minocycline isPrimaryTopicOf Minocycline.