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- naltrexone abstract "The drug combination morphine/naltrexone (trade name Embeda) was an opioid combination pain medication developed by King Pharmaceuticals for use in moderate to severe pain. The active ingredients were morphine sulfate and naltrexone hydrochloride; morphine being an opioid receptor agonist and naltrexone an opioid receptor antagonist. It is a schedule 2 controlled substance, and was intended for long-term pain caused by malignancy or where lower tiers of the pain management ladder have already been exhausted, and where medications such as oxycodone would otherwise have been indicated.Embeda capsules are formulated with morphine pellets and an inner core containing naltrexone. The purpose of this formulation was to prevent people from crushing the tablet for intravenous injection or intranasal ingestion. If crushed, the naltrexone would mix with the morphine and competitively antagonizes morphine's physiological effects. Ingested orally and intact, the inner core encapsulating the naltrexone is not digestible in the gastrointestinal tract.However, King Pharmaceuticals voluntarily recalled Embeda in 2011 after complaints from the FDA in regards to King Pharmaceuticals omitting information regarding the potentially fatal reaction if crushed and swallowed and also for making unsubstantiated claims regarding Embeda's reduced abuse potential.".
- naltrexone wikiPageID "25012978".
- naltrexone wikiPageRevisionID "561719727".
- naltrexone class Opioid.
- naltrexone class Opioid_antagonist.
- naltrexone component "Morphine sulfate".
- naltrexone component "Naltrexone".
- naltrexone hasPhotoCollection naltrexone.
- naltrexone legalUs "Schedule II".
- naltrexone pregnancyUs "C".
- naltrexone routesOfAdministration "Oral".
- naltrexone tradename "Embeda".
- naltrexone type "combo".
- naltrexone verifiedrevid "416646931".
- naltrexone subject Category:Combination_drugs.
- naltrexone subject Category:Opiates.
- naltrexone subject Category:Opioid_antagonists.
- naltrexone subject Category:Semisynthetic_opioids.
- naltrexone type Agent114778436.
- naltrexone type CausalAgent100007347.
- naltrexone type CombinationDrugs.
- naltrexone type Drug103247620.
- naltrexone type Matter100020827.
- naltrexone type Narcotic103808564.
- naltrexone type Opiate103850746.
- naltrexone type Opiates.
- naltrexone type PhysicalEntity100001930.
- naltrexone type Substance100020090.
- naltrexone type Drug.
- naltrexone type FunctionalSubstance.
- naltrexone comment "The drug combination morphine/naltrexone (trade name Embeda) was an opioid combination pain medication developed by King Pharmaceuticals for use in moderate to severe pain. The active ingredients were morphine sulfate and naltrexone hydrochloride; morphine being an opioid receptor agonist and naltrexone an opioid receptor antagonist.".
- naltrexone label "Morphine/naltrexone".
- naltrexone sameAs m.09gcnb2.
- naltrexone sameAs Q17126485.
- naltrexone sameAs Q17126485.
- naltrexone sameAs naltrexone.
- naltrexone wasDerivedFrom naltrexone?oldid=561719727.
- naltrexone isPrimaryTopicOf naltrexone.