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- Mosapride abstract "Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist. The major active metabolite of mosapride, known as M1, additionally acts as a 5HT3 antagonist. which accelerates gastric emptying throughout the whole of the gastrointestinal tract in humans, and is used for the treatment of gastritis, gastro-oesophageal reflux disease, functional dyspepsia and irritable bowel syndrome. It is recommended to be taken on an empty stomach (i.e. at least one hour before food or two hours after food).In addition to its prokinetic properties, mosapride also exerts anti-inflammatory effects on the gastrointestinal tract which may contribute to some of its therapeutic effects. Mosapride also promotes neurogenesis in the gastrointestinal tract which may prove useful in certain bowel disorders. The neurogenesis is due to mosapride's effect on the 5-HT4 receptor where it acts as an agonist.Its common side effects include dry mouth, abdominal pain, dizziness, headache, insomnia, malaise, nausea, diarrhoea and sometimes constipation. Unlike some other prokinetic agents, mosapride has little effect on potassium channels, no effect on hERG transfected cells, and no effect on cardiovascular function that could be detected in tests on humans. Due to the pharmacokinetics of mosapride, it would take 1,000 - 3,000 times the therapeutic dose to elicit cardiovascular effects.".
- Mosapride atcPrefix "none".
- Mosapride casNumber "112885-41-3".
- Mosapride fdaUniiCode "I8MFJ1C0BY".
- Mosapride iupacName "(RS)-4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}benzamide".
- Mosapride pubchem "119584".
- Mosapride thumbnail Mosapride.png?width=300.
- Mosapride wikiPageID "13565496".
- Mosapride wikiPageRevisionID "600700938".
- Mosapride atcPrefix "none".
- Mosapride c "21".
- Mosapride casNumber "112885".
- Mosapride chembl "60889".
- Mosapride chemspiderid "106780".
- Mosapride cl "1".
- Mosapride f "1".
- Mosapride h "25".
- Mosapride hasPhotoCollection Mosapride.
- Mosapride image "3".
- Mosapride inchi "1".
- Mosapride inchikey "YPELFRMCRYSPKZ-UHFFFAOYAO".
- Mosapride iupacName "-4".
- Mosapride iupharLigand "242".
- Mosapride kegg "D08236".
- Mosapride molecularWeight "421.893".
- Mosapride n "3".
- Mosapride o "3".
- Mosapride pubchem "119584".
- Mosapride smiles "Clc1ccCNCC3OCCNC3".
- Mosapride stdinchi "1".
- Mosapride stdinchikey "YPELFRMCRYSPKZ-UHFFFAOYSA-N".
- Mosapride unii "I8MFJ1C0BY".
- Mosapride verifiedfields "changed".
- Mosapride verifiedrevid "462255663".
- Mosapride width "180".
- Mosapride subject Category:Benzamides.
- Mosapride subject Category:Morpholines.
- Mosapride subject Category:Motility_stimulants.
- Mosapride subject Category:Organochlorides.
- Mosapride subject Category:Organofluorides.
- Mosapride subject Category:Phenol_ethers.
- Mosapride subject Category:Serotonin_receptor_agonists.
- Mosapride type Abstraction100002137.
- Mosapride type Cognition100023271.
- Mosapride type Element114840755.
- Mosapride type Information105816287.
- Mosapride type Matter100020827.
- Mosapride type MotilityStimulants.
- Mosapride type Part113809207.
- Mosapride type PhenolEthers.
- Mosapride type PhysicalEntity100001930.
- Mosapride type PsychologicalFeature100023100.
- Mosapride type Quintessence114847103.
- Mosapride type Relation100031921.
- Mosapride type Stimulation105827684.
- Mosapride type Substance100019613.
- Mosapride type Drug.
- Mosapride type DrugProduct.
- Mosapride type FunctionalSubstance.
- Mosapride comment "Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist. The major active metabolite of mosapride, known as M1, additionally acts as a 5HT3 antagonist. which accelerates gastric emptying throughout the whole of the gastrointestinal tract in humans, and is used for the treatment of gastritis, gastro-oesophageal reflux disease, functional dyspepsia and irritable bowel syndrome. It is recommended to be taken on an empty stomach (i.e.".
- Mosapride label "Mosapride".
- Mosapride label "Mosapride".
- Mosapride label "モサプリド".
- Mosapride sameAs Mosapride.
- Mosapride sameAs モサプリド.
- Mosapride sameAs m.03c9j_x.
- Mosapride sameAs Q68566.
- Mosapride sameAs Q68566.
- Mosapride sameAs Mosapride.
- Mosapride wasDerivedFrom Mosapride?oldid=600700938.
- Mosapride depiction Mosapride.png.
- Mosapride isPrimaryTopicOf Mosapride.