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- Nabil_Seidah abstract "Nabil G. Seidah, CM OQ FRSC (born 1949) is a Québécois scientist. Born in Egypt, he was educated at Cairo University, and subsequently at Georgetown University where he obtained his Ph.D in 1973. He emigrated to Canada and has been working at the Clinical Research Institute of Montreal (IRCM) since 1974. He is the director of the laboratory of Biochemical Neuroendocrinology.Dr. Seidah discovered and cloned seven (PC1, PC2, PC4, PC5, PC7, SKI-1 and PCSK9) of the nine known enzymes belonging to the convertase family. During this period, he also greatly contributed to demonstrating that the proteolysis by the proprotein convertases is a wide mechanism that also concerns “non-neuropeptide” proteins such as growth factors, α-integrins, receptors, enzymes, membrane-bound transcription factors, and bacterial and viral proteins. Recently, he showed that point mutations in the PCSK9 gene cause dominant familial hypercholesterolemia, likely because of a gain of function related to the ability of PCSK9 to enhance the degradation of cell surface receptors, such as the low-density lipoprotein receptor.".
- Nabil_Seidah birthDate "1949".
- Nabil_Seidah birthYear "1949".
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- Nabil_Seidah dateOfBirth "1949".
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- Nabil_Seidah name "Seidah, Nabil".
- Nabil_Seidah shortDescription "Canadian scientist".
- Nabil_Seidah description "Canadian scientist".
- Nabil_Seidah description "Canadian scientist".
- Nabil_Seidah subject Category:1949_births.
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- Nabil_Seidah comment "Nabil G. Seidah, CM OQ FRSC (born 1949) is a Québécois scientist. Born in Egypt, he was educated at Cairo University, and subsequently at Georgetown University where he obtained his Ph.D in 1973. He emigrated to Canada and has been working at the Clinical Research Institute of Montreal (IRCM) since 1974. He is the director of the laboratory of Biochemical Neuroendocrinology.Dr.".
- Nabil_Seidah label "Nabil Seidah".
- Nabil_Seidah label "Nabil Seidah".
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- Nabil_Seidah name "Nabil Seidah".
- Nabil_Seidah name "Seidah, Nabil".
- Nabil_Seidah surname "Seidah".