Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Nicorandil> ?p ?o. }
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- Nicorandil abstract "Nicorandil is a vasodilatory drug used to treat angina. It is marketed under the trade names Ikorel (in the United Kingdom, Australia and most of Europe), Angedil (in Romania, Poland), Dancor (in Switzerland), Nikoran,PCA (in India), Aprior (in the Philippines), Nitorubin (in Japan), and Sigmart (in Japan, South Korea and Taiwan). Nicorandil is not available in the United States.Angina is chest pain that results from episodes of transient myocardial ischemia. This can be caused by diseases such as atherosclerosis, coronary artery disease and aortic stenosis. Angina commonly arises from vasospasm of the coronary arteries. There are multiple mechanisms causing the increased smooth muscle contraction involved in coronary vasospasm, including increased Rho-kinase activity. Increased levels of Rho-kinase inhibit myosin phosphatase activity, leading to increased calcium sensitivity and hypercontraction. Rho-kinase also decreases nitric oxide synthase activity, which reduces nitric oxide concentrations. Lower levels of nitric oxide are present in spastic coronary arteries. L-type calcium channel expression increases in spastic vascular smooth muscle cells, which could result in excessive calcium influx, and hypercontraction.Nicorandil is an anti-angina medication that has the dual properties of a nitrate and K+ATP channel agonist. In humans, the nitrate action of nicorandil dilates the large coronary arteries at low plasma concentrations. At high plasma concentrations nicorandil reduces coronary vascular resistance, which is associated with increased K+ATP channel opening.".
- Nicorandil atcPrefix "C01".
- Nicorandil atcSuffix "DX16".
- Nicorandil bioavailability "75.0".
- Nicorandil casNumber "65141-46-0".
- Nicorandil fdaUniiCode "260456HAM0".
- Nicorandil iupacName "2-[(pyridin-3-ylcarbonyl)amino]ethyl nitrate".
- Nicorandil pubchem "47528".
- Nicorandil thumbnail Nicorandil.svg?width=300.
- Nicorandil wikiPageID "4820671".
- Nicorandil wikiPageRevisionID "604875335".
- Nicorandil atcPrefix "1.0".
- Nicorandil atcSuffix "DX16".
- Nicorandil bioavailability "75".
- Nicorandil c "8".
- Nicorandil casNumber "65141".
- Nicorandil chembl "284906".
- Nicorandil chemspiderid "43240".
- Nicorandil eliminationHalfLife "3600.0".
- Nicorandil excretion Kidney.
- Nicorandil h "9".
- Nicorandil hasPhotoCollection Nicorandil.
- Nicorandil inchi "1".
- Nicorandil inchikey "LBHIOVVIQHSOQN-UHFFFAOYAO".
- Nicorandil iupacName "2".
- Nicorandil iupharLigand "2411".
- Nicorandil kegg "D01810".
- Nicorandil legalUk "POM".
- Nicorandil metabolism Liver.
- Nicorandil molecularWeight "211.175".
- Nicorandil n "3".
- Nicorandil o "4".
- Nicorandil pregnancyAu "B3".
- Nicorandil proteinBound "25.0".
- Nicorandil pubchem "47528".
- Nicorandil routesOfAdministration "Oral".
- Nicorandil smiles "O=Cc1cccnc1".
- Nicorandil stdinchi "1".
- Nicorandil stdinchikey "LBHIOVVIQHSOQN-UHFFFAOYSA-N".
- Nicorandil unii "260456".
- Nicorandil verifiedrevid "417579163".
- Nicorandil subject Category:Alkyl_nitrates.
- Nicorandil subject Category:Amides.
- Nicorandil subject Category:Antianginals.
- Nicorandil subject Category:Potassium_channel_openers.
- Nicorandil subject Category:Pyridines.
- Nicorandil subject Category:Vasodilators.
- Nicorandil type Abstraction100002137.
- Nicorandil type AlkylNitrates.
- Nicorandil type Amide114724264.
- Nicorandil type Amides.
- Nicorandil type Base114618253.
- Nicorandil type Beginning107290905.
- Nicorandil type Chemical114806838.
- Nicorandil type Compound114818238.
- Nicorandil type Event100029378.
- Nicorandil type Happening107283608.
- Nicorandil type Material114580897.
- Nicorandil type Matter100020827.
- Nicorandil type Nitrate115015501.
- Nicorandil type Opener107326369.
- Nicorandil type OrganicCompound114727670.
- Nicorandil type Part113809207.
- Nicorandil type PhysicalEntity100001930.
- Nicorandil type PotassiumChannelOpeners.
- Nicorandil type PsychologicalFeature100023100.
- Nicorandil type Pyridine114692510.
- Nicorandil type Pyridines.
- Nicorandil type Relation100031921.
- Nicorandil type Start107325190.
- Nicorandil type Substance100019613.
- Nicorandil type YagoPermanentlyLocatedEntity.
- Nicorandil type Drug.
- Nicorandil type DrugProduct.
- Nicorandil type FunctionalSubstance.
- Nicorandil comment "Nicorandil is a vasodilatory drug used to treat angina. It is marketed under the trade names Ikorel (in the United Kingdom, Australia and most of Europe), Angedil (in Romania, Poland), Dancor (in Switzerland), Nikoran,PCA (in India), Aprior (in the Philippines), Nitorubin (in Japan), and Sigmart (in Japan, South Korea and Taiwan). Nicorandil is not available in the United States.Angina is chest pain that results from episodes of transient myocardial ischemia.".
- Nicorandil label "Nicorandil".
- Nicorandil label "Nicorandil".
- Nicorandil label "Nicorandil".
- Nicorandil label "Nikorandil".
- Nicorandil label "Никорандил".
- Nicorandil label "シグマート".
- Nicorandil sameAs Nicorandil.
- Nicorandil sameAs シグマート.
- Nicorandil sameAs Nikorandil.
- Nicorandil sameAs Nicorandil.
- Nicorandil sameAs m.0cpmck.
- Nicorandil sameAs Q862989.
- Nicorandil sameAs Q862989.
- Nicorandil sameAs Nicorandil.
- Nicorandil wasDerivedFrom Nicorandil?oldid=604875335.
- Nicorandil depiction Nicorandil.svg.
- Nicorandil isPrimaryTopicOf Nicorandil.