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- Nitrogen_mustard abstract "The nitrogen mustards are cytotoxic chemotherapy agents similar to mustard gas. Although their common use is medicinal, in principle these compounds can also be deployed as chemical warfare agents. Nitrogen mustards are nonspecific DNA alkylating agents. Nitrogen mustard gas was stockpiled by several nations during the Second World War, but it was never used in combat. As with all types of mustard gas, nitrogen mustards are powerful and persistent blister agents and the main examples (HN1, HN2, HN3, see below) are therefore classified as Schedule 1 substances within the Chemical Weapons Convention. Production and use is therefore strongly restricted.During WWII nitrogen mustards were studied at Yale University and classified human clinical trials of nitrogen mustards for the treatment of lymphoma started in December 1942. Also during WWII, an incident during the air raid on Bari, Italy, led to the release of mustard gas that affected several hundred soldiers and civilians. Medical examination of the survivors showed a decreased number of lymphocytes. After WWII was over, the Bari incident and the Yale group's studies eventually converged prompting a search for other similar compounds. Due to its use in previous studies, the nitrogen mustard known as "HN2" became the first chemotherapy drug mustine.Nitrogen mustards are not related to the mustard plant or its pungent essence, allyl isothiocyanate: the name comes from the pungent smell of chemical weapons preparations.".
- Nitrogen_mustard thumbnail Ethyl-S.svg?width=300.
- Nitrogen_mustard wikiPageID "2257791".
- Nitrogen_mustard wikiPageRevisionID "596978823".
- Nitrogen_mustard hasPhotoCollection Nitrogen_mustard.
- Nitrogen_mustard subject Category:Blister_agents.
- Nitrogen_mustard subject Category:IARC_Group_2A_carcinogens.
- Nitrogen_mustard subject Category:Nitrogen_mustards.
- Nitrogen_mustard comment "The nitrogen mustards are cytotoxic chemotherapy agents similar to mustard gas. Although their common use is medicinal, in principle these compounds can also be deployed as chemical warfare agents. Nitrogen mustards are nonspecific DNA alkylating agents. Nitrogen mustard gas was stockpiled by several nations during the Second World War, but it was never used in combat.".
- Nitrogen_mustard label "Azotiprite".
- Nitrogen_mustard label "Iperyty azotowe".
- Nitrogen_mustard label "Loste".
- Nitrogen_mustard label "Moutarde azotée".
- Nitrogen_mustard label "Nitrogen mustard".
- Nitrogen_mustard label "Stikstofmosterd".
- Nitrogen_mustard label "Производные бис-β-хлорэтиламина".
- Nitrogen_mustard label "ナイトロジェンマスタード".
- Nitrogen_mustard label "氮芥类".
- Nitrogen_mustard sameAs Dusíkatý_yperit.
- Nitrogen_mustard sameAs Loste.
- Nitrogen_mustard sameAs Moutarde_azotée.
- Nitrogen_mustard sameAs Azotiprite.
- Nitrogen_mustard sameAs ナイトロジェンマスタード.
- Nitrogen_mustard sameAs 머스터드_질소.
- Nitrogen_mustard sameAs Stikstofmosterd.
- Nitrogen_mustard sameAs Iperyty_azotowe.
- Nitrogen_mustard sameAs m.06zt6l.
- Nitrogen_mustard sameAs Q414004.
- Nitrogen_mustard sameAs Q414004.
- Nitrogen_mustard wasDerivedFrom Nitrogen_mustard?oldid=596978823.
- Nitrogen_mustard depiction Ethyl-S.svg.
- Nitrogen_mustard isPrimaryTopicOf Nitrogen_mustard.