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- Ohmefentanyl abstract "Ohmefentanyl (β-hydroxy-3-methylfentanyl) was discovered in 1995 and is an extremely potent analgesic drug which selectively binds to the µ-opioid receptor.Ohmefentanyl is one of the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which are used for tranquilizing large animals such as elephants in veterinary medicine. In mouse studies, the most active isomer 3R,4S,βS-ohmefentanyl was 28 times more powerful as a painkiller than fentanyl, the chemical from which it is derived, and 6300 times more effective than morphine. Ohmefentanyl has three stereogenic centers and so has eight stereoisomers, which are named F9201–F9208. Researchers are studying the different pharmaceutical properties of these isomers.The 4"-fluoro analogue (i.e. substituted on the phenethyl ring) of the 3R,4S,βS isomer of ohmefentanyl is one of the most potent opioid agonists yet discovered, possessing an analgesic potency approximately 18,000-fold greater than morphine. Other analogues with potency higher than that of ohmefentanyl itself include the 2'-fluoro derivative (i.e. substituted on the aniline phenyl ring), and derivatives where the N-propionyl group was replaced by N-methoxyacetyl or 2-furamide groups, or a carboethoxy group is added to the 4-position of the piperidine ring. The latter is listed as being up to 30,000 times more potent than morphine.".
- Ohmefentanyl atcPrefix "none".
- Ohmefentanyl casNumber "78995-14-9".
- Ohmefentanyl iupacName "N-[(3R,4S)-1-[(2S)-2-hydroxy-2-phenyl-ethyl] -3-methyl-4-piperidyl]-N-phenyl-propanamide".
- Ohmefentanyl pubchem "10474095".
- Ohmefentanyl thumbnail Ohmefentanyl.svg?width=300.
- Ohmefentanyl wikiPageID "10163770".
- Ohmefentanyl wikiPageRevisionID "586749913".
- Ohmefentanyl atcPrefix "none".
- Ohmefentanyl c "23".
- Ohmefentanyl casNumber "78995".
- Ohmefentanyl chemspiderid "8649506".
- Ohmefentanyl h "30".
- Ohmefentanyl hasPhotoCollection Ohmefentanyl.
- Ohmefentanyl inchi "1".
- Ohmefentanyl inchikey "FRPRNNRJTCONEC-BVYCBKJFBF".
- Ohmefentanyl iupacName "N-[-1-[-2-hydroxy-2-phenyl-ethyl] -3-methyl-4-piperidyl]-N-phenyl-propanamide".
- Ohmefentanyl molecularWeight "366.497".
- Ohmefentanyl n "2".
- Ohmefentanyl o "2".
- Ohmefentanyl pubchem "10474095".
- Ohmefentanyl smiles "O=CNC3=CC=CC=C3".
- Ohmefentanyl stdinchi "1".
- Ohmefentanyl stdinchikey "FRPRNNRJTCONEC-BVYCBKJFSA-N".
- Ohmefentanyl verifiedrevid "447755463".
- Ohmefentanyl width "200".
- Ohmefentanyl subject Category:Alcohols.
- Ohmefentanyl subject Category:Anilides.
- Ohmefentanyl subject Category:Mu-opioid_agonists.
- Ohmefentanyl subject Category:Piperidines.
- Ohmefentanyl subject Category:Propionamides.
- Ohmefentanyl subject Category:Synthetic_opioids.
- Ohmefentanyl type Abstraction100002137.
- Ohmefentanyl type Agent114778436.
- Ohmefentanyl type Alcohol107884567.
- Ohmefentanyl type Alcohols.
- Ohmefentanyl type Beverage107881800.
- Ohmefentanyl type CausalAgent100007347.
- Ohmefentanyl type Drug103247620.
- Ohmefentanyl type DrugOfAbuse103248958.
- Ohmefentanyl type Fluid114939900.
- Ohmefentanyl type Food100021265.
- Ohmefentanyl type Liquid114940386.
- Ohmefentanyl type Matter100020827.
- Ohmefentanyl type Part113809207.
- Ohmefentanyl type PhysicalEntity100001930.
- Ohmefentanyl type Relation100031921.
- Ohmefentanyl type Substance100019613.
- Ohmefentanyl type Substance100020090.
- Ohmefentanyl type Drug.
- Ohmefentanyl type DrugProduct.
- Ohmefentanyl type FunctionalSubstance.
- Ohmefentanyl comment "Ohmefentanyl (β-hydroxy-3-methylfentanyl) was discovered in 1995 and is an extremely potent analgesic drug which selectively binds to the µ-opioid receptor.Ohmefentanyl is one of the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which are used for tranquilizing large animals such as elephants in veterinary medicine.".
- Ohmefentanyl label "Ohmefentanyl".
- Ohmefentanyl label "Ohmefentanyl".
- Ohmefentanyl label "Β-hydroksy-3-metylofentanyl".
- Ohmefentanyl label "Бета-гидрокси-3-метилфентанил".
- Ohmefentanyl sameAs Ohmefentanyl.
- Ohmefentanyl sameAs Β-hydroksy-3-metylofentanyl.
- Ohmefentanyl sameAs m.01xm8lc.
- Ohmefentanyl sameAs Q905028.
- Ohmefentanyl sameAs Q905028.
- Ohmefentanyl sameAs DB01570.
- Ohmefentanyl sameAs Ohmefentanyl.
- Ohmefentanyl wasDerivedFrom Ohmefentanyl?oldid=586749913.
- Ohmefentanyl depiction Ohmefentanyl.svg.
- Ohmefentanyl isPrimaryTopicOf Ohmefentanyl.