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- PIK3CG abstract "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PIK3CG gene.This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.".
- PIK3CG entrezgene "5294".
- PIK3CG wikiPageID "14194017".
- PIK3CG wikiPageRevisionID "545026927".
- PIK3CG hasPhotoCollection PIK3CG.
- PIK3CG requireManualInspection "no".
- PIK3CG summaryText "This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.".
- PIK3CG updateCitations "yes".
- PIK3CG updatePage "yes".
- PIK3CG updateProteinBox "yes".
- PIK3CG updateSummary "yes".
- PIK3CG subject Category:Cell_signaling.
- PIK3CG type Biomolecule.
- PIK3CG type Protein.
- PIK3CG type BiologicalObject.
- PIK3CG comment "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PIK3CG gene.This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring.".
- PIK3CG label "PI3K Gamma".
- PIK3CG label "PIK3CG".
- PIK3CG sameAs PIK3CG.
- PIK3CG sameAs m.03cxdzm.
- PIK3CG sameAs Q4046199.
- PIK3CG sameAs Q4046199.
- PIK3CG sameAs 2404.
- PIK3CG sameAs 3464.
- PIK3CG wasDerivedFrom PIK3CG?oldid=545026927.
- PIK3CG isPrimaryTopicOf PIK3CG.