Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PRKACA> ?p ?o. }
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- PRKACA abstract "cAMP-dependent protein kinase catalytic subunit alpha is an enzyme that in humans is encoded by the PRKACA gene.cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the Protein kinase A (PKA), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of PKA is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.".
- PRKACA entrezgene "5566".
- PRKACA wikiPageID "13641056".
- PRKACA wikiPageRevisionID "600161194".
- PRKACA hasPhotoCollection PRKACA.
- PRKACA requireManualInspection "no".
- PRKACA summaryText "cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the Protein kinase A , which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of PKA is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.".
- PRKACA updateCitations "yes".
- PRKACA updatePage "yes".
- PRKACA updateProteinBox "yes".
- PRKACA updateSummary "yes".
- PRKACA type Biomolecule.
- PRKACA type Protein.
- PRKACA type BiologicalObject.
- PRKACA comment "cAMP-dependent protein kinase catalytic subunit alpha is an enzyme that in humans is encoded by the PRKACA gene.cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the Protein kinase A (PKA), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of PKA is a tetramer composed of two regulatory and two catalytic subunits.".
- PRKACA label "PRKACA".
- PRKACA sameAs m.03ccrf2.
- PRKACA sameAs Q7120326.
- PRKACA sameAs Q7120326.
- PRKACA sameAs 2504.
- PRKACA sameAs 3427.
- PRKACA wasDerivedFrom PRKACA?oldid=600161194.
- PRKACA isPrimaryTopicOf PRKACA.