Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PRKCI> ?p ?o. }
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- PRKCI abstract "Protein kinase C iota type is an enzyme that in humans is encoded by the PRKCI gene.This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.".
- PRKCI entrezgene "5584".
- PRKCI wikiPageExternalLink pmidlookup?view=long&pmid=8627654.
- PRKCI wikiPageExternalLink pmidlookup?view=long&pmid=8524286.
- PRKCI wikiPageExternalLink pmidlookup?view=long&pmid=9566925.
- PRKCI wikiPageExternalLink pmidlookup?view=long&pmid=8226978.
- PRKCI wikiPageExternalLink pmidlookup?view=long&pmid=2139676.
- PRKCI wikiPageID "14723076".
- PRKCI wikiPageRevisionID "592854129".
- PRKCI hasPhotoCollection PRKCI.
- PRKCI requireManualInspection "no".
- PRKCI summaryText "This gene encodes a member of the protein kinase C family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.".
- PRKCI updateCitations "yes".
- PRKCI updatePage "yes".
- PRKCI updateProteinBox "yes".
- PRKCI updateSummary "yes".
- PRKCI type Biomolecule.
- PRKCI type Protein.
- PRKCI type BiologicalObject.
- PRKCI comment "Protein kinase C iota type is an enzyme that in humans is encoded by the PRKCI gene.This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol.".
- PRKCI label "PRKCI".
- PRKCI sameAs m.03gvk97.
- PRKCI sameAs Q7120343.
- PRKCI sameAs Q7120343.
- PRKCI wasDerivedFrom PRKCI?oldid=592854129.
- PRKCI isPrimaryTopicOf PRKCI.