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- PTPN11 abstract "Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D) or protein-tyrosine phosphatase 2C (PTP-2C) is an enzyme that in humans is encoded by the PTPN11 gene. PTPN11 is a protein tyrosine phosphatase (PTP) Shp2.PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.".
- PTPN11 entrezgene "5781".
- PTPN11 wikiPageExternalLink br.fcgi?book=gene&part=noonan.
- PTPN11 wikiPageID "6062401".
- PTPN11 wikiPageRevisionID "602094719".
- PTPN11 hasPhotoCollection PTPN11.
- PTPN11 subject Category:EC_3.1.3.
- PTPN11 subject Category:Human_genes.
- PTPN11 type Biomolecule.
- PTPN11 type Protein.
- PTPN11 type BiologicalObject.
- PTPN11 comment "Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D) or protein-tyrosine phosphatase 2C (PTP-2C) is an enzyme that in humans is encoded by the PTPN11 gene. PTPN11 is a protein tyrosine phosphatase (PTP) Shp2.PTPN11 is a member of the protein tyrosine phosphatase (PTP) family.".
- PTPN11 label "PTPN11".
- PTPN11 sameAs m.0fn5hd.
- PTPN11 sameAs Q7120997.
- PTPN11 sameAs Q7120997.
- PTPN11 wasDerivedFrom PTPN11?oldid=602094719.
- PTPN11 isPrimaryTopicOf PTPN11.