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- metoclopramide abstract "Paracetamol/metoclopramide hydrochloride is an oral fixed dose combination prescription medication containing the analgesic paracetamol (500 mg) and the anti-emetic metoclopramide hydrochloride (5 mg). Formulated as a tablet and as sachets of a water-soluble powder, it is sold under the trade name Paramax by Sanofi-Synthelabo, and in Switzerland as Migraeflux MCP [1], in Australia it is sold as Meteclomax and Anagraine.The combination is used to treat the symptoms of migraine, both to relieve headache (the analgesic) and to treat associated nausea and vomiting (the antiemetic). In addition to its direct anti-emetic effect metoclopramide also stimulates gastric emptying (prokinetic), which is often delayed during migraine attacks, and accelerates the absorption of paracetamol. However the improvement in paracetamol absorption has been questioned.The combination of metoclopramide to the paracetamol has been shown to enhance the analgesia relief when used to treat the pain of arthritis.Whilst the individual component drugs may be prescribed individually, as a combination, it is only available as the branded Paramax preparation in the UK. In the UK there are only two other combination analgesics with antiemetics (i.e., anti-nausea) products available: MigraMax (aspirin with metoclopramide) and the over-the-counter drug Migraleve (paracetamol and codeine for analgesia, with buclizine as the antiemetic). The role for these products is between just the use of simple analgesics (paracetamol or ibuprofen) and the triptan class of drugs; although the latter are not options during pregnancy. In the elderly although triptans are generally avoided, so too are antiemetics such as metoclopramide due to higher risks of side effects. In Australia and New Zealand, the combination is available without prescription from pharmacies.".
- metoclopramide wikiPageExternalLink www.migraeflux.org.
- metoclopramide wikiPageID "17054537".
- metoclopramide wikiPageRevisionID "596396950".
- metoclopramide class Analgesic.
- metoclopramide class Dopamine_antagonist.
- metoclopramide component "Metoclopramide".
- metoclopramide component "Paracetamol".
- metoclopramide hasPhotoCollection metoclopramide.
- metoclopramide legalAu "S3".
- metoclopramide legalStatus "OTC".
- metoclopramide legalUk "POM".
- metoclopramide routesOfAdministration "Oral".
- metoclopramide type "combo".
- metoclopramide verifiedrevid "394193879".
- metoclopramide subject Category:Analgesics.
- metoclopramide subject Category:Antiemetics.
- metoclopramide subject Category:Antimigraine_drugs.
- metoclopramide subject Category:Combination_drugs.
- metoclopramide type Agent114778436.
- metoclopramide type Analgesic102707683.
- metoclopramide type Analgesics.
- metoclopramide type Antiemetic102719750.
- metoclopramide type Antiemetics.
- metoclopramide type AntimigraineDrugs.
- metoclopramide type CausalAgent100007347.
- metoclopramide type CombinationDrugs.
- metoclopramide type Drug103247620.
- metoclopramide type Matter100020827.
- metoclopramide type Medicine103740161.
- metoclopramide type PhysicalEntity100001930.
- metoclopramide type Substance100020090.
- metoclopramide type Drug.
- metoclopramide type DrugProduct.
- metoclopramide type FunctionalSubstance.
- metoclopramide comment "Paracetamol/metoclopramide hydrochloride is an oral fixed dose combination prescription medication containing the analgesic paracetamol (500 mg) and the anti-emetic metoclopramide hydrochloride (5 mg).".
- metoclopramide label "Paracetamol/metoclopramide".
- metoclopramide sameAs m.0416xbh.
- metoclopramide sameAs Q7133847.
- metoclopramide sameAs Q7133847.
- metoclopramide sameAs 4168.
- metoclopramide sameAs metoclopramide.
- metoclopramide wasDerivedFrom metoclopramide?oldid=596396950.
- metoclopramide isPrimaryTopicOf metoclopramide.